CAS: 876755-27-0 - (αS,4R)-4-[4-(2-Hydroxyethoxy)phenyl]-2,5-dioxo-N-[4-(1-oxopropyl)-2-thiazolyl]-α-[(1S)-1-phenylethyl]-1-imidazolidineacetamide

Formula: C₂₇H₂₈N₄O₆S

InChI: InChI=1S/C27H28N4O6S/c1-3-21(33)20-15-38-26(28-20)30-24(34)23(16(2)17-7-5-4-6-8-17)31-25(35)22(29-27(31)36)18-9-11-19(12-10-18)37-14-13-32/h4-12,15-16,22-23,32H,3,13-14H2,1-2H3,(H,29,36)(H,28,30,34)/t16-,22+,23-/m0/s1

InChI key: InChIKey=RKKBPPTYPGTSEA-FNVCAUGXSA-N

SMILES: O=C1NC(C(=O)N1C(C(=O)NC2=NC(=CS2)C(=O)CC)C(C=3C=CC=CC3)C)C4=CC=C(OCCO)C=C4

Synonyms:

• RO 4927350
• 1-Imidazolidineacetamide, 4-[4-(2-hydroxyethoxy)phenyl]-2,5-dioxo-N-[4-(1-oxopropyl)-2-thiazolyl]-α-[(1S)-1-phenylethyl]-, (αS,4R)-
• (αS,4R)-4-[4-(2-Hydroxyethoxy)phenyl]-2,5-dioxo-N-[4-(1-oxopropyl)-2-thiazolyl]-α-[(1S)-1-phenylethyl]-1-imidazolidineacetamide
• Ro 4927350
• (2S,3S)-2-[(4R)-4-[4-(2-Hydroxyethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]-3-phenyl-N-(4-propionylthiazol-2-yl)butanamide

(2S,3S)-2-((R)-4-(4-(2-Hydroxyethoxy)phenyl)-2,5-dioxo-imidazolidin-1-yl)-3-phenyl-N-(4-propionylthiazol-2-yl)butyramide

CAS: 876755-27-0

(2S,3S)-2-((R)-4-(4-(2-Hydroxyethoxy)phenyl)-2,5-dioxo-imidazolidin-1-yl)-3-phenyl-N-(4-propionylthiazol-2-yl)butyramide is an aromatic ketone that has been shown to inhibit mitogen activated protein kinase …

• Formula: C₂₇H₂₈N₄O₆S
• Purity: Min. 95%
• Molecular weight: 536.6 g/mol

RO4927350

CAS: 876755-27-0

RO4927350 is a potent, selective MEK1/2 inhibitor, blocking MAPK pathway in vitro/vivo and showing notable …

• Formula: C₂₇H₂₈N₄O₆S
• Color and Shape: Solid
• Molecular weight: 536.6