CAS 87679-37-6
:Trandolapril
Description:
Trandolapril is an angiotensin-converting enzyme (ACE) inhibitor primarily used in the treatment of hypertension and heart failure. It is a white to off-white crystalline powder that is soluble in water and organic solvents. The chemical formula of Trandolapril is C24H34N2O5, and it has a molecular weight of approximately 426.54 g/mol. The substance works by inhibiting the ACE enzyme, which plays a crucial role in the renin-angiotensin-aldosterone system, leading to vasodilation and reduced blood pressure. Trandolapril is typically administered orally and is often prescribed in combination with other antihypertensive agents. Its pharmacokinetics include a prodrug nature, as it is converted to its active form, Trandolaprilat, in the body. Common side effects may include dizziness, fatigue, and gastrointestinal disturbances. As with other ACE inhibitors, it is contraindicated in patients with a history of angioedema related to previous ACE inhibitor therapy and during pregnancy due to potential risks to the fetus.
Formula:C24H34N2O5
InChI:InChI=1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1
InChI key:InChIKey=VXFJYXUZANRPDJ-WTNASJBWSA-N
SMILES:C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2[C@@]3([C@@](C[C@H]2C(O)=O)(CCCC3)[H])[H]
Synonyms:- 1H-Indole-2-carboxylic acid, 1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-, (2S,3aR,7aS)-
- Trandolapril
- (2s,3ar,7as)-1-[(2s)-2-[[(1s)-1-ethoxycarbonyl-3-phenyl-propyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
- 1H-Indole-2-carboxylic acid, 1-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-, [2S-[1[R*(R*)],2α,3aα,7aβ]]-
- RU 44570
- (2S,3aR,7aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid (non-preferred name)
- (2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid
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Found 14 products.
TRANDOLAPRIL CRS
CAS:TRANDOLAPRIL CRSFormula:C24H34N2O5Color and Shape:PowderMolecular weight:430.5372Trandolapril
CAS:TrandolaprilFormula:C24H34N2O5Purity:99.6%Color and Shape:WhiteMolecular weight:430.24677Trandolapril
CAS:Cardiovascular drugs, not elsewhere specified or includedFormula:C24H34N2O5Color and Shape:White PowderMolecular weight:430.24677Trandolapril
CAS:Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.Formula:C24H34N2O5Purity:99.70% - 99.83%Color and Shape:White PowderMolecular weight:430.54Trandolapril
CAS:Formula:C24H34N2O5Purity:≥ 98.0%Color and Shape:White crystalline powderMolecular weight:430.54Trandolapril
CAS:Controlled Product<p>Applications An antihypertensive. Angiotensin converting enzyme (ACE) inhibitor.<br>References Brown, N.L., et al.: Eur. J. Pharmacol., 148, 79 (1988), Kober, L., et al.: N. Engl. J. Med., 333, 1670 (1995), Malik, R.A., et al.: Lancet, 352, 1978 (1998)<br></p>Formula:C24H34N2O5Color and Shape:NeatMolecular weight:430.54Trandolapril
CAS:<p>Inhibitor of angiotensin-converting enzyme</p>Formula:C24H34N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:430.54 g/molTrandolapril-d3
CAS:Controlled Product<p>Applications Trandolapril-d3, is the labeled analogue of Trandolapril (T713500), an antihypertensive. Angiotensin converting enzyme (ACE) inhibitor.<br>References Brown, N.L., et al.: Eur. J. Pharmacol., 148, 79 (1988), Kober, L., et al.: N. Engl. J. Med., 333, 1670 (1995), Malik, R.A., et al.: Lancet, 352, 1978 (1998)<br></p>Formula:C24D3H31N2O5Color and Shape:NeatMolecular weight:433.556
