CAS 87719-32-2

Etarotene

Description:

Etarotene, with the CAS number 87719-32-2, is a synthetic retinoid, which is a class of compounds related to vitamin A. It is primarily characterized by its ability to modulate gene expression and influence cellular differentiation and proliferation, making it of interest in dermatological and oncological research. Etarotene exhibits anti-inflammatory and anti-proliferative properties, which have been explored in the treatment of various skin conditions, including acne and psoriasis, as well as certain types of cancer. The compound is typically administered topically or systemically, depending on the therapeutic application. Its mechanism of action involves binding to retinoic acid receptors, leading to changes in gene transcription that promote normal skin cell turnover and reduce abnormal cell growth. While it has shown promise in clinical settings, the safety profile and potential side effects, such as skin irritation or teratogenic effects, are important considerations in its use. Overall, etarotene represents a significant area of interest in the development of targeted therapies in dermatology and oncology.

Formula: C₂₅H₃₂O₂S

InChI: InChI=1S/C25H32O2S/c1-7-28(26,27)21-11-8-19(9-12-21)16-18(2)20-10-13-22-23(17-20)25(5,6)15-14-24(22,3)4/h8-13,16-17H,7,14-15H2,1-6H3/b18-16+

InChI key: InChIKey=UDAZCXVIYSIEFX-FBMGVBCBSA-N

SMILES: CC1(C)C=2C(C(C)(C)CC1)=CC=C(\C(=C\C3=CC=C(S(CC)(=O)=O)C=C3)\C)C2

Synonyms:

• 6-[(1E)-2-[4-(Ethylsulfonyl)phenyl]-1-methylethenyl]-1,2,3,4-tetrahydro-1,1,4,4-tetramethylnaphthalene
• Naphthalene, 6-[2-[4-(ethylsulfonyl)phenyl]-1-methylethenyl]-1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-, (E)-
• Naphthalene, 6-[(1E)-2-[4-(ethylsulfonyl)phenyl]-1-methylethenyl]-1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-
• Arotinoid sulfone
• Ro 15-1570

Etarotene

CAS: 87719-32-2

Etarotene

Purity: ≥98%

Molecular weight: 396.59g/mol

Ref: 54-BUP07816

Etarotene

CAS: 87719-32-2

Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a

Formula: C₂₅H₃₂O₂S

Purity: 99.58% - 99.98%

Color and Shape: Solid

Molecular weight: 396.59

Ref: TM-T25393