CAS 877773-32-5

3-[1-[(2,4-Dichlorophenyl)methyl]-6-(trifluoromethyl)-1H-indazol-3-yl]-2-propenoic acid

Description:

3-[1-[(2,4-Dichlorophenyl)methyl]-6-(trifluoromethyl)-1H-indazol-3-yl]-2-propenoic acid, with the CAS number 877773-32-5, is a synthetic organic compound characterized by its complex structure, which includes an indazole core substituted with a dichlorophenyl group and a trifluoromethyl group. This compound features a propenoic acid moiety, contributing to its potential reactivity and biological activity. The presence of the trifluoromethyl group often enhances lipophilicity and metabolic stability, while the dichlorophenyl group may influence its interaction with biological targets. Such compounds are typically investigated for their pharmacological properties, including potential anti-inflammatory or anticancer activities. The specific arrangement of functional groups suggests that it may engage in various chemical interactions, making it a candidate for further research in medicinal chemistry. As with many synthetic compounds, safety and handling precautions are essential due to potential toxicity or environmental impact.

Formula: C₁₈H₁₁Cl₂F₃N₂O₂

InChI: InChI=1S/C18H11Cl2F3N2O2/c19-12-3-1-10(14(20)8-12)9-25-16-7-11(18(21,22)23)2-4-13(16)15(24-25)5-6-17(26)27/h1-8H,9H2,(H,26,27)

InChI key: InChIKey=KYYQMVUKYQCSQY-UHFFFAOYSA-N

SMILES: C(N1C=2C(C(C=CC(O)=O)=N1)=CC=C(C(F)(F)F)C2)C3=C(Cl)C=C(Cl)C=C3

Synonyms:

• 3-[1-(2,4-Dichlorobenzyl)-6-(trifluoromethyl)-1H-indazol-3-yl]acrylic acid
• Gamendazole
• 2-Propenoic acid, 3-[1-[(2,4-dichlorophenyl)methyl]-6-(trifluoromethyl)-1H-indazol-3-yl]-
• 3-[1-[(2,4-Dichlorophenyl)methyl]-6-(trifluoromethyl)-1H-indazol-3-yl]-2-propenoic acid

Gamendazole

CAS: 877773-32-5

Gamendazole is a novel drug candidate for male contraception. It has been shown to reduce fertility in male rats without affecting testosterone levels.

Formula: C₁₈H₁₁Cl₂F₃N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 415.19

Ref: TM-T24084