CAS 877877-35-5

N-{4-[(2-tert-butylphenyl)sulfonyl]phenyl}-2,3,4-trihydroxy-5-[2-(propan-2-yl)benzyl]benzamide

Description:

N-{4-[(2-tert-butylphenyl)sulfonyl]phenyl}-2,3,4-trihydroxy-5-[2-(propan-2-yl)benzyl]benzamide, with the CAS number 877877-35-5, is a complex organic compound characterized by its multi-functional structure. It features a sulfonamide group, which is known for its role in various biological activities, and multiple hydroxyl groups that contribute to its potential solubility and reactivity. The presence of bulky tert-butyl and isopropyl groups suggests that the compound may exhibit significant steric hindrance, influencing its interaction with biological targets. The compound's aromatic rings provide stability and may facilitate π-π stacking interactions, which are important in drug design and molecular recognition. Additionally, the hydroxyl groups can participate in hydrogen bonding, enhancing its potential as a pharmacophore. Overall, this compound's unique structural features may contribute to its biological activity, making it a candidate for further investigation in medicinal chemistry and related fields.

Formula: C₃₃H₃₅NO₆S

InChI: InChI=1/C33H35NO6S/c1-20(2)25-11-7-6-10-21(25)18-22-19-26(30(36)31(37)29(22)35)32(38)34-23-14-16-24(17-15-23)41(39,40)28-13-9-8-12-27(28)33(3,4)5/h6-17,19-20,35-37H,18H2,1-5H3,(H,34,38)

SMILES: CC(C)c1ccccc1Cc1cc(c(c(c1O)O)O)C(=O)Nc1ccc(cc1)S(=O)(=O)c1ccccc1C(C)(C)C

Synonyms:

• Tw-37
• N-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide
• N-[4-[(2-tert-Butylphenyl)sulfonyl]phenyl]-2,3,4-trihydroxy-5-[(2-isopropylphenyl)methyl]benzamide TW-37
• N-[4-[(2-tert-Butylphenyl)sulfonyl]phenyl]-2,3,4-trihydroxy-5-[(2-isopropylphenyl)methyl]benzamide
• CS-299
• Bcl-2 Inhibitor N-[4-[(2-tert-Butylphenyl)sulfonyl]phenyl]-2,3,4-trihydroxy-5-[(2-isopropylphenyl)methyl]benzamide
• Benzamide, N-[4-[[2-(1,1-dimethylethyl)phenyl]sulfonyl]phenyl]-2,3,4-trihydroxy-5-[[2-(1-methylethyl)phenyl]methyl]-
• TW37;TW 37
• TW-37 USP/EP/BP
• N-{4-[(2-tert-butylbenzene)sulfonyl]phenyl}-2,3,4-trihydroxy-5-[(2-isopropylphenyl)methyl]benzamide
• 5-(2-isopropylbenzyl)-N-(4-(2-tert-butylphenylsulfonyl)phenyl)-2,3,4-trihydroxybenzamide

N-{4-[(2-tert-butylbenzene)sulfonyl]phenyl}-2,3,4-trihydroxy-5-[(2-isopropylphenyl)methyl]benzamide

CAS: 877877-35-5

Formula: C₃₃H₃₅NO₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 573.6991

Ref: IN-DA003SN1

TW-37

CAS: 877877-35-5

TW-37

Purity: ≥95%

Molecular weight: 573.7g/mol

Ref: 54-BUP05404

TW-37

CAS: 877877-35-5

TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).

Formula: C₃₃H₃₅NO₆S

Purity: 97.06% - ≥95%

Color and Shape: Solid

Molecular weight: 573.7

Ref: TM-T6281