CAS 87789-49-9

Pyrimidine,5-fluoro-2-(1-piperazinyl)-

Description:

Pyrimidine, 5-fluoro-2-(1-piperazinyl)-, is a chemical compound characterized by its pyrimidine ring structure, which is a six-membered aromatic heterocycle containing two nitrogen atoms at positions 1 and 3. The presence of a fluorine atom at the 5-position of the pyrimidine ring enhances its biological activity and lipophilicity. The 2-position features a piperazine moiety, which is a saturated six-membered ring containing two nitrogen atoms, contributing to the compound's pharmacological properties. This compound is often studied for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting various biological pathways. Its structural features suggest it may exhibit interactions with biological receptors or enzymes, making it of interest in drug design. Additionally, the presence of both the fluorine atom and the piperazine group may influence its solubility, stability, and overall reactivity, which are critical factors in the evaluation of its therapeutic potential.

Formula: C₈H₁₁FN₄

InChI: InChI=1S/C8H11FN4/c9-7-5-11-8(12-6-7)13-3-1-10-2-4-13/h5-6,10H,1-4H2

InChI key: InChIKey=GXXFECFLKWGTNP-UHFFFAOYSA-N

SMILES: FC=1C=NC(=NC1)N2CCNCC2

Synonyms:

• 1-(5-Fluoro-2-pyrimidinyl)piperazine
• 5-Fluoro-2-(1-piperazinyl)pyrimidine
• 5-Fluoro-2-(piperazin-1-yl)pyrimidine
• Mj 14676
• Pyrimidine, 5-fluoro-2-(1-piperazinyl)-
• 5-FLUORO-2-PIPERAZIN-1-YLPYRIMIDINE
• 2-ethylthio-5-fluoropyrimidine
• Pyrimidine, 5-fluoro-2-(1-piperazinyl)- (9CI)