Photofrin, or porfimer sodium, is a photosensitizing agent primarily used in photodynamic therapy for the treatment of certain types of cancer, particularly esophageal and lung cancers. It is a derivative of porphyrin, a class of organic compounds characterized by their large, planar structures and ability to absorb light. Photofrin exhibits strong absorption in the red region of the spectrum, which is advantageous for therapeutic applications as it allows for deeper tissue penetration. Upon activation by light, Photofrin generates reactive oxygen species that can induce cell death in targeted cancer cells while sparing surrounding healthy tissue. The substance is typically administered intravenously and is known for its relatively low toxicity. However, it can cause photosensitivity, necessitating precautions to avoid exposure to sunlight or bright indoor light following treatment. Its pharmacokinetics involve accumulation in tumor tissues, enhancing its efficacy in localized cancer treatment. Overall, Photofrin represents a significant advancement in cancer therapy, combining the principles of chemistry and biology to improve patient outcomes.

Photofrin Porfimer sodium

87806-31-3: Photofrin, or porfimer sodium, is a photosensitizing agent primarily used in photodynamic therapy for the treatment of certain types of cancer, particularly esophageal and lung cancers. It is a derivative of porphyrin, a class of organic compounds characterized by their large, planar structures and ability to absorb light. Photofrin exhibits strong absorption in the red region of the spectrum, which is advantageous for therapeutic applications as it allows for deeper tissue penetration. Upon activation by light, Photofrin generates reactive oxygen species that can induce cell death in targeted cancer cells while sparing surrounding healthy tissue. The substance is typically administered intravenously and is known for its relatively low toxicity. However, it can cause photosensitivity, necessitating precautions to avoid exposure to sunlight or bright indoor light following treatment. Its pharmacokinetics involve accumulation in tumor tissues, enhancing its efficacy in localized cancer treatment. Overall, Photofrin represents a significant advancement in cancer therapy, combining the principles of chemistry and biology to improve patient outcomes.

<p>Porfimer sodium, a sodium salt with photodynamic properties, targets tumor cells and induces cytotoxicity with 630 nm laser activation.</p>

CAS 87806-31-3

Photofrin Porfimer sodium

Porfimer Sodium

Ref: TM-T34112