CAS 878141-96-9

4-[2-[[5-Methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine

Description:

4-[2-[[5-Methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine, with the CAS number 878141-96-9, is a synthetic organic compound characterized by its complex structure, which includes a morpholine ring, a pyrazole moiety, and a naphthalene substituent. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity, making it of interest in medicinal chemistry and drug development. The presence of the morpholine ring suggests it may interact with biological targets, potentially influencing pharmacological activity. The naphthalene group can contribute to hydrophobic interactions, while the pyrazole unit may participate in hydrogen bonding and other molecular interactions. Overall, this compound's unique structural features may confer specific chemical reactivity and biological properties, warranting further investigation for applications in pharmaceuticals or agrochemicals. As with any chemical substance, safety data and handling precautions should be considered, particularly regarding its potential toxicity and environmental impact.

Formula: C₂₀H₂₃N₃O₂

InChI: InChI=1S/C20H23N3O2/c1-16-14-20(25-13-10-22-8-11-24-12-9-22)21-23(16)19-7-6-17-4-2-3-5-18(17)15-19/h2-7,14-15H,8-13H2,1H3

InChI key: InChIKey=DGPGXHRHNRYVDH-UHFFFAOYSA-N

SMILES: CC=1N(C2=CC3=C(C=C2)C=CC=C3)N=C(OCCN4CCOCC4)C1

Synonyms:

• E 52862
• MR-309
• 4-[2-[[5-Methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine
• S1RA
• Morpholine, 4-[2-[[5-methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]-

S1RA

CAS: 878141-96-9

Formula: C₂₀H₂₃N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 337.4155

Ref: IN-DA00GTC5

S1RA

CAS: 878141-96-9

S1RA

Purity: ≥98%

Molecular weight: 337.42g/mol

Ref: 54-BUP01760

S1RA

CAS: 878141-96-9

S1RA (E-52862)(E-52862) is a potent, selective antagonist of the sigma-1 receptor (σ1R, Ki=17 nM), demonstrating significant selectivity over the sigma-2

Formula: C₂₀H₂₃N₃O₂

Purity: 99.45%

Color and Shape: Solid

Molecular weight: 337.42

Ref: TM-T1865

E 52862 (S1RA)

CAS: 878141-96-9

E 52862 (S1RA) is a monoclonal antibody that targets the α2δ subunit of voltage-gated calcium channels. It blocks the binding of ATP and reduces neuronal excitability, providing antinociception without causing dependence or addiction. E 52862 has been shown to be an effective treatment for diabetic neuropathy in vivo models. The drug has also been shown to have a sub-effective dose, which may reduce its side effects. E 52862's receptor activity may be due to its ability to inhibit glutamate release and cyclin D2 expression, which are both involved in pain transmission.

Formula: C₂₀H₂₃N₃O₂

Purity: Min. 95%

Molecular weight: 337.42 g/mol

Ref: 3D-BE177449