
CAS 87860-39-7
:Fostriecin sodium
Description:
Fostriecin sodium, with the CAS number 87860-39-7, is a chemical compound that exhibits properties characteristic of a phosphonate ester. It is primarily known for its role as an antibiotic and has garnered interest in the field of cancer research due to its potential as an antitumor agent. Fostriecin sodium functions by inhibiting protein phosphatases, which are crucial for various cellular processes, including cell division and signal transduction. This inhibition can lead to the disruption of cancer cell growth and proliferation. The compound is typically presented as a sodium salt, enhancing its solubility in aqueous solutions, which is beneficial for biological applications. In terms of stability, fostriecin sodium is sensitive to hydrolysis, necessitating careful handling and storage conditions. Its pharmacological profile includes a range of biological activities, making it a subject of ongoing research in medicinal chemistry and pharmacology. Overall, fostriecin sodium represents a significant compound with potential therapeutic applications, particularly in oncology.
Formula:C19H26NaO9P
InChI:InChI=1/C19H27O9P.Na/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20;/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26);/q;+1/p-1/b3-2-,6-4+,8-5-,12-11+;/t15-,16+,17+,19+;/m0./s1
InChI key:InChIKey=JUSDOSJWBHHCBI-IAVQPKKASA-N
SMILES:[C@H]([C@](/C=C/[C@@H]1OC(=O)C=CC1)(C)O)(C[C@H](/C=C\C=C/C=C/CO)O)OP(=O)(O)O.[Na]
Synonyms:- (2Z,5R,6E,8R,9R,11R,12Z,14Z,16E)-8,11,18-Trihydroxy-9-(phosphonooxy)-octadeca-2,6,12,14,16-pentaeno-5-lactone monosodium salt
- 2H-Pyran-2-one, 5,6-dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraen-1-yl]-, sodium salt (1:1), (6R)-
- 2H-Pyran-2-one, 5,6-dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-, monosodium salt, (6R)-
- Cl-1565A
- Fostriecin sodium
- Pd-110161
- sodium (1R,3R,4Z,6Z,8E)-3,10-dihydroxy-1-{(1R,2E)-1-hydroxy-1-methyl-3-[(2R)-6-oxo-3,6-dihydro-2H-pyran-2-yl]prop-2-en-1-yl}deca-4,6,8-trien-1-yl hydrogen phosphate
- Fostriecin sodium salt from Streptomyces pulveraceus >=98% (HPLC)
- FOSTRIECIN SODIUM SALT
- cl1565asodiumsalt
- PHOSPHOTRIENIN
- ci920sodiumsalt
- (6R)-5,6-DIHYDRO-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-TRIHYDROXY-3-METHYL-4-(PHOSPHONOOXY)-1,7,9,11-TRIDECATETRAENYL]-2H-PYRAN-2-ONE SODIUM SALT
- FOSTRIECIN
- Human FST Protein, Fc Tag
- antibioticcl1565asodiumsalt
- fostriecin sodium salt from streptomyces pulveraceus
- FOSTRIECIN SODIUM SALT USP/EP/BP
- Fostriecin, Sodium Salt, Streptomyces pulveraceous - CAS 87860-39-7 - Calbiochem
- (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-onesodiumsalt
- FST
- FOSTRIECIN, SODIUM SALT, STREPTOMYCES PULVERACEOUS
- CL-920
- (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one monosodium salt
- FST344
- antibioticci920sodiumsalt
- See more synonyms
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Found 3 products.
Fostriecin
CAS:Formula:C19H26NaO9PPurity:≥ 95.0%Color and Shape:Colourless solidMolecular weight:452.4Fostriecin sodium salt
CAS:<p>Fostriecin sodium salt is an immunosuppressant that is used to prevent organ rejection in patients who have received a transplanted organ. It binds to antibodies and prevents their binding to antigens on the transplanted organ, thus preventing antibody response. Fostriecin sodium salt has been shown to be effective in reducing the incidence of autoimmune disease, cancer, and graft-versus-host disease. The effective dose for this drug is 5mg/kg/day. Fostriecin sodium salt may be administered orally or intravenously. This immunosuppressant does not alter the regulatory immune system or suppress the body's natural immunity.</p>Formula:C19H26O9PNaPurity:Min. 95%Molecular weight:452.37 g/mol


