
CAS 87865-78-9
:N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine
Description:
N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine is a modified nucleoside that features a guanosine base with specific chemical modifications. The presence of the isobutyryl group at the N2 position enhances its lipophilicity and may influence its biological activity, potentially affecting interactions with enzymes or receptors. The 3',5'-O-dialkylated siloxane moiety introduces a unique siloxane framework, which can provide stability against hydrolysis and enhance solubility in organic solvents. This compound is likely to exhibit properties typical of nucleosides, such as the ability to participate in hydrogen bonding and base pairing, while the modifications may alter its pharmacokinetic and pharmacodynamic profiles. Its structural complexity suggests potential applications in medicinal chemistry, particularly in the development of antiviral or anticancer agents. The CAS number 87865-78-9 serves as a unique identifier for this compound, facilitating its recognition in chemical databases and literature. Overall, this substance represents an interesting intersection of organic chemistry and biochemistry, with potential implications in drug design and development.
Formula:C26H45N5O7Si2
Synonyms:- N2-isobutyryl-3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-guanosine
- Guanosine, N-(2-methyl-1-oxopropyl)-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-
- N2-iBu-3',5'-TIPDS-Gr
- 3',5'-TIPS-ibu-rG
- N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
- N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine
- N2-ISOBUTYRYL-3,5-TIPPS-GUANOSINE
- 3',5'-TIPS-N-ibu-guanosine
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Found 3 products.
N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine
CAS:Formula:C26H45N5O7Si2Purity:98%Color and Shape:SolidMolecular weight:595.8358N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
CAS:N-(9-((6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramidePurity:97%Molecular weight:595.85g/molN2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine
CAS:<p>N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-diyl)guanosine is a nucleoside that is activated by phosphorylation. It has been shown to be an inhibitor of cancer cell growth and proliferation in vitro. This compound was also found to inhibit the expression of two oncogenes (c-MYC and c-Ki67) and induce the expression of the tumor suppressor gene p53. This nucleoside is synthesized from 2'-deoxyadenosine monophosphate (2'-DAMP) with a modified DNA synthesis protocol.</p>Formula:C26H45N5O7Si2Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:595.84 g/mol



