CAS 879-18-5

1-Naphthoyl chloride

Description:

1-Naphthoyl chloride, with the CAS number 879-18-5, is an aromatic acyl chloride derived from naphthalene. It is characterized by its white to pale yellow crystalline solid form, which is typically volatile and has a distinct odor. This compound is known for its reactivity, particularly due to the presence of the acyl chloride functional group, which makes it a potent electrophile. It readily undergoes nucleophilic acyl substitution reactions, making it useful in organic synthesis for the introduction of the 1-naphthoyl group into various substrates. 1-Naphthoyl chloride is soluble in organic solvents such as dichloromethane and ether but is generally insoluble in water. It is important to handle this compound with care, as it can be corrosive and may cause irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment, are essential when working with this chemical.

Formula: C₁₁H₇ClO

InChI: InChI=1S/C11H7ClO/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H

InChI key: InChIKey=NSNPSJGHTQIXDO-UHFFFAOYSA-N

SMILES: C(Cl)(=O)C=1C2=C(C=CC1)C=CC=C2

Synonyms:

• 1-(Chlorocarbonyl)naphthalene
• 1-Naphthalenecarboxylic acid chloride
• 1-Naphthaloyl chloride
• 1-Naphthoic acid chloride
• 1-Naphthoyl chloride
• 1-Naphthylcarbonyl chloride
• Naphthalene-1-Carbonyl Chloride
• Nsc 9841
• Timtec-Bb Sbb006741
• alpha-Naphthoyl chloride
• α-Naphthoyl chloride

1-Naphthoyl Chloride

CAS: 879-18-5

Formula: C₁₁H₇ClO

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Orange to Green clear liquid

Molecular weight: 190.63

Ref: 3B-N0047

1-Naphthoyl chloride, 98%

CAS: 879-18-5

1-Naphthoyl chloride has been used as derivatization reagent in analysis of short-chained dodecyl alcohol ethoxylates and dodecyl alcohol by solid-phase extraction combined with dispersive liquid-liquid micro extraction method, as fluorescent labeling reagent in determination of T-2 and HT-2 toxins

Formula: C₁₁H₇ClO

Purity: 98%

Color and Shape: Clear pale yellow to yellow to pale brown to orange-brown or pale purple, Liquid

Molecular weight: 190.63

Ref: 02-A14460

1-Naphthoyl chloride

CAS: 879-18-5

Formula: C₁₁H₇ClO

Purity: 97%

Color and Shape: Solid

Molecular weight: 190.6257

Ref: IN-DA003EJI

1-Naphthoyl chloride

CAS: 879-18-5

1-Naphthoyl chloride

Formula: C₁₁H₇ClO

Purity: 98%

Color and Shape: light orange to brown. low melting solid

Molecular weight: 190.63g/mol

Ref: 54-OR7500

1-Naphthoyl Chloride

CAS: 879-18-5

Applications 1-Naphthoyl Chloride acts as a reagent in the preparation of tetrandrine derivatives as antitumor agents against human hepatocellular carcinoma. Identification of acylthiourea derivatives as potent Plk1 PBD inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lan, J., et al.: Eur. J. Med. Chem., 127, 554 (2017); Yun, T., et al.: Eur. J. Med. Chem., 124, 229 (2016)

Formula: C₁₁H₇ClO

Color and Shape: Neat

Molecular weight: 190.63

Ref: TR-N497040

naphthalene-1-carbonyl chloride

CAS: 879-18-5

Formula: C₁₁H₇ClO

Purity: 95.0%

Color and Shape: Liquid

Molecular weight: 190.63

Ref: 10-F358329

1-Naphthoyl chloride

CAS: 879-18-5

1-Naphthoyl chloride is a metabolite of 1-naphthol. It has been used in the synthesis of steroidal alkaloids, including the anti-inflammatory drug indomethacin and the anesthetic ketamine. 1-Naphthoyl chloride is also a precursor to synthetic cannabinoids, which are substances that have effects similar to those of cannabis but are not derived from marijuana. It binds to receptors on cells that are sensitive to cannaboids. The binding causes changes in cell function and can lead to psychological effects such as paranoia and hallucinations. The detection sensitivity of 1-naphthoyl chloride can be increased by using fluorescence detectors or gravimetric analysis.

Formula: C₁₁H₇ClO

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 190.63 g/mol

Ref: 3D-FN14793