CAS 879487-87-3

4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazole-1-ethanol

Description:

4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazole-1-ethanol, with the CAS number 879487-87-3, is a complex organic compound characterized by its multi-ring structure, which includes pyrazole and pyridine moieties. This compound features a fluorinated phenyl group and an ethanol functional group, contributing to its potential solubility and reactivity. The presence of the fluorine atom may enhance its biological activity and lipophilicity, making it a candidate for pharmaceutical applications. The methyl group on the pyridine ring can influence its electronic properties and steric hindrance, affecting interactions with biological targets. As a pyrazole derivative, it may exhibit various biological activities, including anti-inflammatory or anti-cancer properties, although specific biological data would depend on empirical studies. Overall, this compound's unique structural features suggest it could be of interest in medicinal chemistry and drug development, warranting further investigation into its properties and potential applications.

Formula: C₂₀H₁₈FN₅O

InChI: InChI=1S/C20H18FN5O/c1-13-3-2-4-19(24-13)20-17(11-22-25-20)14-5-6-18(21)16(9-14)15-10-23-26(12-15)7-8-27/h2-6,9-12,27H,7-8H2,1H3,(H,22,25)

InChI key: InChIKey=JQGOCCALXFSRHZ-UHFFFAOYSA-N

SMILES: CC1=NC(C=2C(=CNN2)C3=CC(=C(F)C=C3)C4=CN(CCO)N=C4)=CC=C1

Synonyms:

• 2-[4-[2-Fluoro-5-[3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazol-1-yl]ethanol
• 1H-Pyrazole-1-ethanol, 4-[2-fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-
• 4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazole-1-ethanol
• 2-[4-[2-Fluoro-5-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]phenyl]pyrazol-1-yl]ethanol
• R 268712

R-268712 

CAS: 879487-87-3

Formula: C₂₀H₁₈FN₅O

Purity: 98%

Color and Shape: Solid

Molecular weight: 363.3882

Ref: IN-DA00GUBH

R-268712

CAS: 879487-87-3

R-268712

Purity: ≥98%

Molecular weight: 363.39g/mol

Ref: 54-BUP09238

2-(4-(2-Fluoro-5-(3-(6-Methylpyridin-2-Yl)-1H-Pyrazol-4-Yl)Phenyl)-1H-Pyrazol-1-Yl)Ethan-1-Ol

CAS: 879487-87-3

2-(4-(2-Fluoro-5-(3-(6-Methylpyridin-2-Yl)-1H-Pyrazol-4-Yl)Phenyl)-1H-Pyrazol-1-Yl)Ethan-1-Ol

Purity: 98%

Molecular weight: 363.39g/mol

Ref: 54-PC108409

R-268712

CAS: 879487-87-3

R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type I receptor orally.

Formula: C₂₀H₁₈FN₅O

Purity: 99.61%

Color and Shape: Solid

Molecular weight: 363.39

Ref: TM-T16708

R-268712

CAS: 879487-87-3

Purity: 98%

Molecular weight: 363.15

Ref: 10-F870126

R-268712

CAS: 879487-87-3

R-268712 is a protein inhibitor that inhibits the activity of growth factor β. It has been shown to be effective in animal models of lung fibrosis, cancer, and eye disorders. R-268712 is administered orally and has been shown to decrease the viscosity of mucus secretions in the lungs, thereby improving lung function. This drug also has pluripotent cell properties and can differentiate into cells of different lineages. R-268712 has no effect on normal cells but inhibits the proliferation of lung fibroblasts and cancer cells in culture.

Formula: C₂₀H₁₈FN₅O

Purity: Min. 95%

Molecular weight: 363.39 g/mol

Ref: 3D-EKB48787