CAS 88-17-5

2-(Trifluoromethyl)aniline

Description:

2-(Trifluoromethyl)aniline, with the CAS number 88-17-5, is an aromatic amine characterized by the presence of a trifluoromethyl group (-CF3) attached to the aniline structure. This compound typically appears as a colorless to pale yellow liquid or solid, depending on the temperature. It has a distinct aromatic odor and is known for its relatively low solubility in water, while being more soluble in organic solvents. The trifluoromethyl group imparts unique electronic properties, enhancing the compound's reactivity and making it useful in various chemical syntheses, particularly in the production of pharmaceuticals and agrochemicals. Additionally, 2-(Trifluoromethyl)aniline exhibits moderate toxicity, necessitating careful handling and appropriate safety measures during use. Its chemical structure contributes to its stability under normal conditions, although it may undergo reactions typical of amines, such as electrophilic aromatic substitution. Overall, this compound is significant in organic chemistry and materials science due to its unique properties and applications.

Formula: C₇H₆F₃N

InChI: InChI=1S/C7H6F3N/c8-7(9,10)5-3-1-2-4-6(5)11/h1-4H,11H2

InChI key: InChIKey=VBLXCTYLWZJBKA-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=C(N)C=CC=C1

Synonyms:

• 2-(Trifluoromethyl)aniline
• 2-(Trifluoromethyl)benzenamine
• 2-Amino-α,α,α-trifluorotoluene
• 2-Aminobenzotrifluoride
• 2-Trifluoromethylaniline
• 2-Trifluoromethylphenylamine
• Benzenamine, 2-(trifluoromethyl)-
• Bis(Trifluoromethylsulfonyloxy)Bismuthanyl Trifluoromethanesulfonate
• NSC 10336
• O-(Trifluoromethyl)aniline
• O-Aminobenzotrifluoride
• o-(Trifluoromethyl)phenylamine
• o-Toluidine, α,α,α-trifluoro-

2-Aminobenzotrifluoride

CAS: 88-17-5

Formula: C₇H₆F₃N

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Light yellow to Light orange clear liquid to slightly cloudy liquid

Molecular weight: 161.13

Ref: 3B-A0433

2-(Trifluoromethyl)aniline, 98%

CAS: 88-17-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₆F₃N

Purity: 98%

Color and Shape: Clear colorless to pale orange, Liquid

Molecular weight: 161.13

Ref: 02-A15072

2-Aminobenzotrifluoride

CAS: 88-17-5

2-Aminobenzotrifluoride

Formula: C₇H₆F₃N

Purity: 97%

Color and Shape: clear. faint yellow liquid

Molecular weight: 161.12g/mol

Ref: 54-PC1020

2-Aminobenzotrifluoride

CAS: 88-17-5

Formula: C₇H₆F₃N

Molecular weight: 161.13

Ref: 7W-GK2485

2-Aminobenzotrifluoride

CAS: 88-17-5

Formula: C₇H₆F₃N

Purity: 99.0%

Color and Shape: Liquid, Colourless liquid

Molecular weight: 161.127

Ref: 10-F001984

Aromatic Comp.-Mix 16 10-20 µg/mL in Methanol

Controlled Product

CAS: 106-40-1, 106-47-8, 108-42-9, 121-69-7, 554-00-7, 608-31-1, 626-43-7, 634-67-3, 636-30-6, 87-62-7, 88-17-5, 95-51-2, 95-53-4, 95-69-2, 95-74-9, 95-76-1, 98-16-8

Formula: C₆H₄Cl₃N

Color and Shape: Mixture

Molecular weight: 196.46

Ref: 04-LA19070016ME

Leflunomide Impurity 13

CAS: 88-17-5

Formula: C₇H₆F₃N

Molecular weight: 161.13

Ref: 4Z-L-0429

2-Aminobenzotrifluoride

Controlled Product

CAS: 88-17-5

Applications 2-Aminobenzotrifluoride is used as a reagent to synthesize thiohydrazides that act as effective antibacterial remedies for chlamydia. 2-Aminobenzotrifluoride is also used as a reagent to synthesize substituted 2-benzothiazolamines which have anticonvulsant activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hays, S., et al.: J. Pharm. Sci., 83, 1425 (1994); Yarovenko, V., et al.: J. Chem. Chemical Eng., 4, 55 (2010)

Formula: C₇H₆F₃N

Color and Shape: Neat

Molecular weight: 161.12

Ref: TR-A630765