CAS 880759-65-9

Morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, [(5a)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazone,dihydrochloride, (5a)-

Description:

Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, also known by its more complex name, is a chemical compound that belongs to the morphinan class of alkaloids. This substance features a morphinan backbone, characterized by a fused ring structure that includes a phenanthrene core. The presence of multiple hydroxyl groups (–OH) indicates that it has significant potential for hydrogen bonding, which can influence its solubility and reactivity. The epoxy group contributes to its reactivity, potentially allowing for further chemical transformations. The propenyl substituent at the 17-position suggests that it may exhibit unique pharmacological properties, possibly affecting its interaction with biological targets. As a hydrazone derivative, it may also display distinct stability and reactivity characteristics compared to its parent morphinan structure. The dihydrochloride form indicates that the compound is likely a salt, which can enhance its solubility in aqueous environments. Overall, this compound's structural features suggest potential applications in medicinal chemistry, particularly in the development of analgesics or other therapeutic agents.

Formula: C₃₈H₄₂N₄O₆ClH

Synonyms:

• Naloxonazinedihydrochloride

Naloxonazine dihydrochloride hydrate

CAS: 880759-65-9

Formula: C₃₈H₄₂N₄O₆·2HCl·xH₂O

Molecular weight: 723.69 (anhydrous)

Ref: 7W-GL1099

Naloxonazine Dihydrochloride

Controlled Product

CAS: 880759-65-9

Applications Naloxonazine Dihydrochloride is a selective μ1 antagonist.
References Isojima, Yasushi., et al.: Proc. Natl. Acad. Sci. U.S.A., 106(37), 15744 (2009);

Formula: C₃₈H₄₂N₄O₆•2(HCl)

Color and Shape: Neat

Molecular weight: 723.68

Ref: TR-N285048

Naloxonazine dihydrochloride

Controlled Product

CAS: 880759-65-9

Naloxonazine dihydrochloride is a ligand for the opioid receptors. It has been shown to bind to the mu, delta, and kappa opioid receptors. Naloxonazine dihydrochloride is used as a diagnostic tool for glioma cells in culture. It has also been shown to block neuropathic pain in rats by modulating the release of neurotransmitters from peripheral nerves. Naloxonazine dihydrochloride inhibits the binding of naltrexone hydrochloride to opioid receptors and may be useful as a treatment for drug addiction.

Formula: C₃₈H₄₂N₄O₆·2HCl

Purity: Min. 95%

Molecular weight: 723.69 g/mol

Ref: 3D-FKB75965

Naloxonazine dihydrochloride

CAS: 880759-65-9

μ1 receptor antagonist

Formula: C₃₈H₄₃ClN₄O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 687.22

Ref: TM-T23053