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CAS 88107-10-2

:

Tomelukast

Description:
Tomelukast, identified by the CAS number 88107-10-2, is a leukotriene receptor antagonist primarily used in the management of asthma and allergic rhinitis. It functions by inhibiting the action of leukotrienes, which are inflammatory mediators that contribute to bronchoconstriction and mucus production. Tomelukast is typically administered orally and is known for its favorable pharmacokinetic profile, including good oral bioavailability and a relatively long half-life, allowing for once-daily dosing. The substance is characterized by its ability to reduce airway inflammation and improve lung function, making it a valuable therapeutic option for patients with respiratory conditions. Additionally, it is generally well-tolerated, with a side effect profile that may include mild gastrointestinal disturbances or headaches. As with any medication, it is essential for patients to consult healthcare professionals for personalized advice and to discuss potential interactions with other medications. Overall, Tomelukast represents an important advancement in the treatment of asthma and allergic conditions.
Formula:C16H22N4O3
InChI:InChI=1S/C16H22N4O3/c1-3-6-13-14(9-8-12(11(2)21)16(13)22)23-10-5-4-7-15-17-19-20-18-15/h8-9,22H,3-7,10H2,1-2H3,(H,17,18,19,20)
InChI key:InChIKey=MWYHLEQJTQJHSS-UHFFFAOYSA-N
SMILES:O(CCCCC=1NN=NN1)C2=C(CCC)C(O)=C(C(C)=O)C=C2
Synonyms:
  • 1-(2-Hydroxy-3-propyl-4-(4-(1H-tetrazol-5-yl)butoxy)phenyl)ethanone
  • 1-{2-hydroxy-3-propyl-4-[4-(2H-tetrazol-5-yl)butoxy]phenyl}ethanone
  • 2'-Hydroxy-3'-propyl-4'-(4-(1H-tetrazol-5-yl)butoxy)acetophenone
  • Acetophenone, 2'-hydroxy-3'-propyl-4-(4-(1H-tetrazol-5-yl)butoxy)-
  • Brn 4238438
  • Ethanone, 1-(2-hydroxy-3-propyl-4-(4-(1H-tetrazol-5-yl)butoxy)phenyl)-
  • Ethanone, 1-[2-hydroxy-3-propyl-4-[4-(2H-tetrazol-5-yl)butoxy]phenyl]-
  • Ly 171883
  • Ly171883
  • Tomelukast [USAN:INN]
  • See more synonyms
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