CAS 881413-29-2

N-[1-[(4,4-Difluorocyclohexyl)methyl]-2-(1,1-dimethylethyl)-1H-benzimidazol-5-yl]ethanesulfonamide

Description:

N-[1-[(4,4-Difluorocyclohexyl)methyl]-2-(1,1-dimethylethyl)-1H-benzimidazol-5-yl]ethanesulfonamide, with CAS number 881413-29-2, is a synthetic organic compound characterized by its complex structure, which includes a benzimidazole core substituted with a sulfonamide group. This compound features a difluorocyclohexyl moiety and a tert-butyl group, contributing to its unique chemical properties. It is typically classified as a sulfonamide, which are known for their diverse biological activities, including antimicrobial and anti-inflammatory effects. The presence of fluorine atoms in its structure may enhance lipophilicity and metabolic stability, potentially influencing its pharmacokinetic profile. The compound's solubility, stability, and reactivity can vary based on environmental conditions and the presence of other chemical species. As with many sulfonamides, it may exhibit specific interactions with biological targets, making it of interest in medicinal chemistry and drug development. However, detailed studies are necessary to fully understand its biological activity and potential applications.

Formula: C₂₀H₂₉F₂N₃O₂S

InChI: InChI=1S/C20H29F2N3O2S/c1-5-28(26,27)24-15-6-7-17-16(12-15)23-18(19(2,3)4)25(17)13-14-8-10-20(21,22)11-9-14/h6-7,12,14,24H,5,8-11,13H2,1-4H3

InChI key: InChIKey=ZAGGGZCIFUQHOH-UHFFFAOYSA-N

SMILES: C(N1C=2C(N=C1C(C)(C)C)=CC(NS(CC)(=O)=O)=CC2)C3CCC(F)(F)CC3

Synonyms:

• AZD-1940
• AZD 1940
• Ethanesulfonamide, N-[1-[(4,4-difluorocyclohexyl)methyl]-2-(1,1-dimethylethyl)-1H-benzimidazol-5-yl]-
• N-[1-[(4,4-Difluorocyclohexyl)methyl]-2-(1,1-dimethylethyl)-1H-benzimidazol-5-yl]ethanesulfonamide
• AZD1940

AZD1940

CAS: 881413-29-2

AZD1940 is a peptide that has been shown to activate a receptor and induce calcium influx in cells. It is not known whether AZD1940 binds to the receptor or if it acts through an allosteric mechanism. This inhibitor of ion channels inhibits protein interactions and prevents the formation of complexes with ligands and receptors.
AZD1940 has been shown to be a potent inhibitor of the human ether-a-go-go related gene (hERG) K+ channel, which is responsible for controlling cardiac repolarization. The inhibition of this channel by AZD1940 leads to prolongation of the QT interval on an electrocardiogram.

Formula: C₂₀H₂₉F₂N₃O₂S

Purity: Min. 95%

Molecular weight: 413.5 g/mol

Ref: 3D-GKB41329

AZD1940

CAS: 881413-29-2

AZD1940 (UNII-0J0035E9FT) is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.

Formula: C₂₀H₂₉F₂N₃O₂S

Purity: 98.68%

Color and Shape: Solid

Molecular weight: 413.52

Ref: TM-T30252