CAS 88150-42-9

Amlodipine

Description:

Amlodipine is a dihydropyridine calcium channel blocker primarily used in the treatment of hypertension and angina. It functions by inhibiting calcium ions from entering vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. Amlodipine is characterized by its chemical formula C20H25ClN2O5S, and it typically appears as a white to off-white crystalline powder. The substance is soluble in organic solvents like ethanol and methanol but has limited solubility in water. Amlodipine exhibits a long half-life, allowing for once-daily dosing, which enhances patient compliance. Its pharmacokinetics are influenced by factors such as age, liver function, and concomitant medications. Common side effects may include peripheral edema, dizziness, and fatigue. As a medication, it is generally well-tolerated, but it is essential for patients to consult healthcare providers for personalized advice and monitoring during treatment.

Formula: C₂₆H₃₁ClN₂O₈S

InChI: InChI=1/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3

InChI key: InChIKey=HTIQEAQVCYTUBX-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1COCCN)C2=C(Cl)C=CC=C2

Synonyms:

• (R,S)-Amlodipine
• 2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
• 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine
• 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
• 3-Ethyl 5-methyl 2(2-aminoethoxymethyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
• 3-O-Ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• Adipin
• Amlodipine base
• Amlopres
• Egiramlon
• Intervask
• Methyl ethyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• Pelmec
• Racemic Amlodipine
• Sofvasc
• Amlodipine
• ethyl methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• AMLODIPINE MM(CRM STANDARD)
• 3,5-pyridinedicarboxylicacid,1,4-dihydro-2-((2-aminoethoxy)methyl)-4-(2-chlor
• Amlodipine ( Amlodipine Benzenesulfonate)
• Amlodipine (base and/or unspecified salts)
• AmlodipineBesylate/Maleate
• Amlodipin
• LOTREL
• 3-ethyl5-methylester
• besylate
• 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2-((2-aminoethoxy)methyl)-4-(2-chlor 3-ethyl 5-methyl ester
• AMLODIPINE (BASE & SALTS)

Amlodipine, 97+%

CAS: 88150-42-9

A calcium channel antagonist with potent antioxidant activity

Formula: C₂₀H₂₅ClN₂O₅

Purity: 97+%

Molecular weight: 408.88

Ref: 02-J62242

Amlodipine

CAS: 88150-42-9

Color and Shape: Neat

Ref: 61-FOR0383.06

Amlodipine

CAS: 88150-42-9

Amlodipine (UK-48340) is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.

Formula: C₂₀H₂₅ClN₂O₅

Purity: 99.33% - 99.60%

Color and Shape: Solid Powder

Molecular weight: 408.88

Ref: TM-T1385

3,​5-​Pyridinedicarboxylic acid, 2-​[(2-​aminoethoxy)​methyl]​-​4-​(2-​chlorophenyl)​-​1,​4-​dihydro-​6-​methyl-​, 3-​ethyl 5-​methyl ester

CAS: 88150-42-9

Formula: C₂₀H₂₅ClN₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 408.8759

Ref: IN-DA00IEZM

Amlodipine

CAS: 88150-42-9

Amlodipine

Purity: ≥98%

Molecular weight: 408.88g/mol

Ref: 54-BUP18604

Amlodipine

CAS: 88150-42-9

Amlodipine

Purity: 98%

Molecular weight: 408.88g/mol

Ref: 54-OR1029436

Amlodipine

CAS: 88150-42-9

Formula: C₂₀H₂₅ClN₂O₅

Molecular weight: 408.88

Ref: 4Z-A-08109

Amlodipine

CAS: 88150-42-9

Formula: C₂₀H₂₅ClN₂O₅

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 408.88

Ref: 7W-GP9536

Amlodipine

Controlled Product

CAS: 88150-42-9

Formula: C₂₀H₂₅ClN₂O₅

Color and Shape: Neat

Molecular weight: 408.88

Ref: 86-MM0383.06

Amlodipine Mesilate

Controlled Product

CAS: 246852-12-0, 88150-42-9

Formula: C₂₀H₂₅ClN₂O₅

Color and Shape: Neat

Molecular weight: 408.88

Ref: 86-MM0592.00

Amlodipine Besylate

CAS: 111470-99-6, 88150-42-9

Formula: C₂₀H₂₅ClN₂O₅·C₆H₅SO₃H

Purity: >98.0%(HPLC)(qNMR)

Color and Shape: White to Dark green powder to crystal

Molecular weight: 567.05

Ref: 3B-A2353

Amlodipine 100 µg/mL in Acetonitrile

CAS: 88150-42-9

Formula: C₂₀H₂₅ClN₂O₅

Color and Shape: Single Solution

Molecular weight: 408.88

Ref: 04-A10240400AL-100

Amlodipine

Controlled Product

CAS: 88150-42-9

Formula: C₂₀H₂₅ClN₂O₅

Color and Shape: Neat

Molecular weight: 408.88

Ref: 04-C10240400

Amlodipine

Controlled Product

CAS: 88150-42-9

Formula: C₂₀H₂₅ClN₂O₅

Color and Shape: Off White

Molecular weight: 408.88

Ref: TR-A633495

Amlodipine base

CAS: 88150-42-9

Inhibits L-type calcium channels; anti-hypertensive; antianginal

Formula: C₂₀H₂₅ClN₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 408.88 g/mol

Ref: 3D-FA61536

Amlodipine

CAS: 88150-42-9

Purity: 98%(HPLC);RG

Molecular weight: 408.145

Ref: 10-F793933

Amlodipine

CAS: 88150-42-9

Inhibits L-type calcium channels; anti-hypertensive; antianginal

Formula: C₂₀H₂₅ClN₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 408.88 g/mol

Ref: 3D-BA164164