CAS 881681-01-2

5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine (2E)-2-butenedioate (1:1)

Description:

5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine (2E)-2-butenedioate (1:1), with CAS number 881681-01-2, is a synthetic organic compound characterized by its complex molecular structure, which includes a pyrrole ring, a fluorophenyl group, and a pyridinylsulfonyl moiety. This compound exhibits properties typical of small organic molecules, such as moderate solubility in polar solvents and potential bioactivity due to its structural features. The presence of the fluorine atom may enhance lipophilicity and influence the compound's interaction with biological targets. The sulfonamide group can impart unique reactivity and stability, while the methanamine component may contribute to its pharmacological profile. Overall, this compound is of interest in medicinal chemistry, particularly for its potential applications in drug development, although specific biological activities and mechanisms of action would require further investigation through empirical studies. As with many synthetic compounds, safety and handling precautions should be observed, given the potential for toxicity or reactivity.

Formula: C₂₁H₂₀FN₃O₆S

InChI: InChI=1S/C17H16FN3O2S.C4H4O4/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14;5-3(6)1-2-4(7)8/h2-9,11-12,19H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key: InChIKey=ROGSHYHKHPCCJW-WLHGVMLRSA-N

SMILES: S(=O)(=O)(N1C(=CC(CNC)=C1)C2=C(F)C=CC=C2)C=3C=CC=NC3.C(=C/C(O)=O)\C(O)=O

Synonyms:

• 1H-Pyrrole-3-methanamine, 5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-, (2E)-2-butenedioate (1:1)
• 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine (2E)-2-butenedioate
• 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine (2E)-2-butenedioate (1:1)
• TAK 438 monofumarate
• Tak-438
• Takecab
• Vocinti
• Vonoprazan fumarate
• Vonaprazan
• TAK438
• 1-(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate
• Vonoprazan FuMarate###NA

Vonoprazan Fumarate

CAS: 881681-01-2

Formula: C₂₁H₂₀FN₃O₆S

Purity: 95%

Color and Shape: Solid

Molecular weight: 461.4634

Ref: IN-DA00H1CR

Vonoprazan Fumarate

CAS: 881681-01-2

Vonoprazan Fumarate

Purity: 98%

Molecular weight: 461.46g/mol

Ref: 54-PC109191

Vonoprazan Fumarate

CAS: 881681-01-2

Formula: C₁₇H₁₆FN₃O₂S·C₄H₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 345.39 116.07

Ref: 4Z-V-051017

Vonoprazan Fumarate

CAS: 881681-01-2

Color and Shape: Neat

Ref: 86-MM3871.01

Vonoprazan Fumarate

CAS: 881681-01-2

Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion.

Formula: C₂₁H₂₀FN₃O₆S

Purity: 98.94%

Color and Shape: Solid

Molecular weight: 461.46

Ref: TM-T21254

Vonoprazan Fumarate

Controlled Product

CAS: 881681-01-2

Applications Vonoprazan fumarate (CAS# 881681-01-2) is a useful research chemical and a ATPase potassium-competitive acid blocker.
References Kondo, M.; et al.: Journal of Biomolecular Screening, 17, 177 (2012).

Formula: C₁₇H₁₆FN₃O₂S·C₄H₄O₄

Color and Shape: White To Off-White

Molecular weight: 461.463

Ref: TR-V767013

Vonoprazan fumarate

CAS: 881681-01-2

Vonoprazan fumarate is a pharmaceutical compound that functions as a potassium-competitive acid blocker (PCAB), which is derived from synthetic sources. It acts by selectively inhibiting the gastric hydrogen-potassium ATPase enzyme, commonly known as the proton pump, located in the stomach lining. This mode of action results in a significant reduction in gastric acid secretion, offering a therapeutic alternative to traditional proton pump inhibitors (PPIs).

Formula: C₁₇H₁₆FN₃O₂S•C₄H₄O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 461.46 g/mol

Ref: 3D-FF102206