CAS 88183-19-1
:Cytidine, 2',3'-dideoxy-2',3'-epithio-
Description:
Cytidine, 2',3'-dideoxy-2',3'-epithio- is a nucleoside analog that is structurally related to cytidine, a component of RNA. This compound features modifications at the 2' and 3' positions of the ribose sugar, specifically the replacement of the hydroxyl groups with sulfur atoms, which imparts unique properties. The presence of the epithio group enhances its stability and alters its interaction with nucleic acid synthesis enzymes. As a dideoxynucleoside, it lacks the hydroxyl groups necessary for the formation of phosphodiester bonds, making it a potent inhibitor of viral replication and a subject of interest in antiviral drug development. Its mechanism of action typically involves incorporation into viral RNA, leading to chain termination during replication. This compound is primarily studied in the context of antiviral therapies, particularly for retroviruses. Safety and handling precautions are essential due to its potential biological activity. Overall, Cytidine, 2',3'-dideoxy-2',3'-epithio- represents a significant area of research in medicinal chemistry and virology.
Formula:C9H11N3O3S
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