CAS 88183-82-8

Guanosine,2'-deoxy-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-

Description:

Guanosine, 2'-deoxy-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]- is a modified nucleoside that features a guanine base linked to a deoxyribose sugar. The presence of the siloxane moiety, specifically the tetrakis(1-methylethyl) group, indicates that this compound has been chemically modified to enhance its stability and solubility, potentially making it useful in various biochemical applications. The siloxane groups can provide unique properties such as increased hydrophobicity and resistance to enzymatic degradation. This compound may be of interest in the fields of molecular biology and medicinal chemistry, particularly in the development of nucleic acid analogs or as a tool for studying nucleic acid interactions. Its CAS number, 88183-82-8, allows for easy identification in chemical databases. Overall, the structural modifications impart specific characteristics that can be leveraged for research and therapeutic purposes.

Formula: C₂₂H₃₉N₅O₅Si₂

3'',5''-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine

CAS: 88183-82-8

Ref: 7W-GN4831

3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine-13C,15N2

Controlled Product

CAS: 88183-82-8

Applications Used in the preparation of nucleotide analogs.

Formula: CC₂₁H₃₉₁₅N₂N₃O₆Si₂

Color and Shape: Neat

Molecular weight: 528.725

Ref: TR-T298512

2'-Deoxy-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine-13C15N2

Controlled Product

CAS: 88183-82-8

Applications 2'-Deoxy-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine-13C15N2 is an isotope labelled intermediate in the preparation of nucleotide analogs.
References Robins, M. J., et al.: J. Am. Chem. Soc., 105, 4059 (1983);

Formula: C₂₁CH₃₉N₃N₂O₅Si₂

Color and Shape: Neat

Molecular weight: 512.73

Ref: TR-D278787

3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine

CAS: 88183-82-8

3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is a nucleoside phosphoramidite that is synthesized by the reaction of 3',5'-O-[Tetrakis(trimethylsiloxy)silyl]guanosine with tetrakis(1-methylethyl) siloxane. It is a novel monophosphate analogue of guanosine and has antiviral, anticancer and activator properties. 3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is not toxic to cells and can be used in the treatment of cancer.

Formula: C₂₂H₃₉N₅O₆Si₂

Purity: Min. 95%

Molecular weight: 525.75 g/mol

Ref: 3D-NT16564