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CAS 88192-98-7

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Myxopyronin A

Description:
Myxopyronin A is a natural antibiotic compound produced by the bacterium *Myxococcus xanthus*. It is characterized by its unique structure, which includes a bicyclic core and various functional groups that contribute to its biological activity. Myxopyronin A primarily acts as an inhibitor of bacterial RNA polymerase, thereby interfering with transcription and ultimately inhibiting bacterial growth. This mechanism makes it a valuable compound in the study of antibiotic resistance and the development of new antimicrobial agents. The substance exhibits a broad spectrum of activity against Gram-positive bacteria, including some strains that are resistant to conventional antibiotics. Additionally, Myxopyronin A has been investigated for its potential therapeutic applications, particularly in treating infections caused by multidrug-resistant pathogens. Its stability and solubility properties are also of interest in pharmaceutical formulations. Overall, Myxopyronin A represents a significant example of natural products with potential clinical relevance in combating bacterial infections.
Formula:C23H31NO6
InChI:InChI=1/C23H31NO6/c1-6-9-15(2)11-12-17(4)21(26)20-18(25)14-19(30-22(20)27)16(3)10-7-8-13-24-23(28)29-5/h8,11-14,16,27H,6-7,9-10H2,1-5H3,(H,24,28)/b13-8+,15-11+,17-12+/t16-/m1/s1
InChI key:InChIKey=UQFNCSLGZUJVQP-JNZIYJEQSA-N
SMILES:C(/C(=C/C=C(/CCC)\C)/C)(=O)C1=C(O)C=C([C@@H](CC/C=C/NC(OC)=O)C)OC1=O
Synonyms:
  • Carbamic acid, [5-[3-(2,5-dimethyl-1-oxo-2,4-octadienyl)-4-hydroxy-2-oxo-2H-pyran-6-yl]-1-hexenyl]-, methyl ester, [R-(E,E,E)]-
  • Carbamic acid, [(1E,5R)-5-[3-[(2E,4E)-2,5-dimethyl-1-oxo-2,4-octadienyl]-4-hydroxy-2-oxo-2H-pyran-6-yl]-1-hexenyl]-, methyl ester
  • Carbamic acid, N-[(1E,5R)-5-[3-[(2E,4E)-2,5-dimethyl-1-oxo-2,4-octadien-1-yl]-4-hydroxy-2-oxo-2H-pyran-6-yl]-1-hexen-1-yl]-, methyl ester
  • Myxopyronin A
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