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CAS 881921-10-4

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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-methyl-L-norvaline

Description:
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-methyl-L-norvaline, commonly referred to as Fmoc-2-methyl-L-norvaline, is a synthetic amino acid derivative primarily used in peptide synthesis and research. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal under mild acidic conditions. The presence of the 2-methyl group in the norvaline structure contributes to its unique steric and electronic properties, influencing the conformation and reactivity of peptides synthesized with this amino acid. Fmoc-2-methyl-L-norvaline is characterized by its relatively high solubility in organic solvents and moderate solubility in water, making it suitable for various biochemical applications. Additionally, it is important in the study of peptide interactions and the development of novel therapeutic agents. As with many synthetic compounds, proper handling and storage conditions are essential to maintain its stability and efficacy in laboratory settings.
Formula:C21H23NO4
InChI:InChI=1S/C21H23NO4/c1-3-12-21(2,19(23)24)22-20(25)26-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18H,3,12-13H2,1-2H3,(H,22,25)(H,23,24)/t21-/m0/s1
InChI key:InChIKey=JJDVDOMASOCGOV-NRFANRHFSA-N
SMILES:C(OC(N[C@@](CCC)(C(O)=O)C)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
Synonyms:
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-methyl-L-norvaline
  • L-Norvaline, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl-
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