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CAS 88296-61-1

:

Medorinone

Description:
Medorinone, with the CAS number 88296-61-1, is a chemical compound that belongs to the class of drugs known as phosphodiesterase inhibitors. It is primarily characterized by its ability to enhance cardiac contractility and improve hemodynamic parameters, making it useful in the treatment of heart failure. Medorinone works by inhibiting the breakdown of cyclic adenosine monophosphate (cAMP), leading to increased intracellular cAMP levels, which in turn promotes vasodilation and improves myocardial function. The compound is typically administered intravenously and has a relatively short half-life, necessitating careful monitoring during treatment. Medorinone may exhibit side effects such as hypotension and arrhythmias, which are important considerations in clinical settings. Its pharmacokinetics and safety profile have been studied in various clinical trials, contributing to its understanding as a therapeutic agent in cardiology. Overall, Medorinone represents a significant option in the management of acute heart failure, although its use may be limited by potential adverse effects and the need for careful patient selection.
Formula:C9H8N2O
InChI:InChI=1/C9H8N2O/c1-6-7-2-3-9(12)11-8(7)4-5-10-6/h2-5H,1H3,(H,11,12)
SMILES:Cc1c2ccc(=O)[nH]c2ccn1
Synonyms:
  • Medorinone [USAN:INN]
  • 5-Methyl-1,6-naphthyridin-2(1H)-one
  • Medorinona
  • Medorinona [Spanish]
  • Medorinonum
  • Medorinonum [Latin]
  • Unii-80X61Y4X0B
  • Win 49,016
  • 1,6-Naphthyridin-2(1H)-one, 5-methyl-
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