CAS 88296-62-2: Transcainide

Description: Transcainide is a chemical compound primarily recognized for its application as an antiarrhythmic agent. It belongs to the class of sodium channel blockers, which are utilized in the management of various cardiac arrhythmias. The compound is characterized by its ability to stabilize cardiac membranes and reduce excitability, thereby helping to restore normal heart rhythm. Transcainide exhibits a moderate lipophilicity, which influences its pharmacokinetic properties, including absorption and distribution within the body. Its mechanism of action involves the inhibition of sodium ion influx during depolarization, leading to a decrease in the rate of action potentials in cardiac tissues. Additionally, transcainide may undergo hepatic metabolism, and its elimination half-life can vary among individuals. As with many pharmacological agents, potential side effects may include dizziness, hypotension, or gastrointestinal disturbances. Due to its specific therapeutic use, transcainide is typically prescribed under careful medical supervision, ensuring that its benefits outweigh any associated risks.

Formula: C₂₂H₃₅N₃O₂

InChI: InChI=1/C22H35N3O2/c1-16-8-7-9-17(2)20(16)23-21(27)22(24(3)4)12-14-25(15-13-22)18-10-5-6-11-19(18)26/h7-9,18-19,26H,5-6,10-15H2,1-4H3,(H,23,27)/t18-,19-/s2

InChI key: InChIKey=MFKCGXDCHAFQQZ-PVIFGLDDNA-N

SMILES: O=C(NC=1C(=CC=CC1C)C)C2(N(C)C)CCN(CC2)C3CCCCC3O

Synonyms:

• rel-4-(Dimethylamino)-N-(2,6-dimethylphenyl)-1-[(1R,2R)-2-hydroxycyclohexyl]-4-piperidinecarboxamide
• Transcainide
• R 54718
• 4-Piperidinecarboxamide, 4-(dimethylamino)-N-(2,6-dimethylphenyl)-1-(2-hydroxycyclohexyl)-, trans-(±)-
• 4-Piperidinecarboxamide, 4-(dimethylamino)-N-(2,6-dimethylphenyl)-1-[(1R,2R)-2-hydroxycyclohexyl]-, rel-

Transcainide

CAS: 88296-62-2

• Purity: ≥98%
• Molecular weight: 373.53g/mol

Transcainide

CAS: 88296-62-2

Transcainide (R 54718), an oral lidocaine-like antiarrhythmic, blocks BTX-activated Na+ channels in heart/muscle.

• Formula: C₂₂H₃₅N₃O₂
• Purity: 99.52%
• Color and Shape: Solid
• Molecular weight: 373.53