CAS 883031-03-6

HC 067047

CAS: 883031-03-6

Formula: C₂₆H₂₈F₃N₃O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 471.5146

Ref: IN-DA00495X

HC-067047

CAS: 883031-03-6

Formula: C₂₆H₂₈F₃N₃O₂

Purity: ≥ 98.0%

Color and Shape: White crystalline powder

Molecular weight: 471.51

Ref: 7W-GL5664

HC-067047

CAS: 883031-03-6

HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .

Formula: C₂₆H₂₈F₃N₃O₂

Purity: 99.45% - 99.97%

Color and Shape: Solid

Molecular weight: 471.51

Ref: TM-T4680

HC-067047

CAS: 883031-03-6

HC-067047 is an experimental drug that has been shown to decrease the intracellular Ca2+ concentration in various cell types, including neurons. This agent also inhibits the influx of Ca2+ ions through voltage-gated channels and blocks the release of Ca2+ from intracellular stores. HC-067047 is being investigated for chronic cough as it has been shown to reduce this symptom in a guinea pig model of asthma. In vitro studies have shown that HC-067047 is not active against protozoa or bacteria but does inhibit the growth of tumor cells. The mechanism of action for HC-067047 is not fully elucidated, but it may act by inhibiting ion transport proteins such as TRPV4, Toll-like receptor, or Ryanodine receptor. HC-067047 has also been found to increase MMP9 activity and inhibit production of cytokines such as IL-6 and TNFα.

Formula: C₂₆H₂₈F₃N₃O₂

Purity: Min. 95%

Molecular weight: 471.51 g/mol

Ref: 3D-IKB03103