CAS 883065-90-5

4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-nitrothiazol-2-yl)sulfanyl-1,2,4-triazol-3-ol

Description:

4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(5-nitrothiazol-2-yl)sulfanyl-1,2,4-triazol-3-ol, with CAS number 883065-90-5, is a chemical compound characterized by its complex structure, which includes a triazole ring, a benzodioxin moiety, and a nitrothiazole group. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity, making it of interest in pharmaceutical research. The presence of the sulfanyl group may contribute to its reactivity and interactions with biological targets. Its unique combination of functional groups suggests potential applications in medicinal chemistry, particularly in the development of antimicrobial or antifungal agents. Additionally, the nitro group may enhance its pharmacological properties, while the triazole ring is often associated with diverse biological activities. Overall, this compound represents a class of heterocyclic compounds that are valuable in drug discovery and development.

Formula: C₁₃H₉N₅O₅S₂

InChI: InChI=1/C13H9N5O5S2/c19-11-15-16-12(25-13-14-6-10(24-13)18(20)21)17(11)7-1-2-8-9(5-7)23-4-3-22-8/h1-2,5-6H,3-4H2,(H,15,19)

SMILES: c1cc2c(cc1n1c(nnc1Sc1ncc(N(=O)=O)s1)O)OCCO2

Synonyms:

• 3H-1,2,4-Triazol-3-one, 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-
• 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-4,5-dihydro-1H-1,2,4-triazol-5-one
• 4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-2,4-dihydro-3H-1,2,4-triazol-3-one
• 4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-3H-1,2,4-triazol-3-one
• JNK Inhibitor X, BI-78D3
• CS-1070
• 4-(2,3-Dihydrobenzol[b][1,4]dioxin-6-yl)-5-(5-nitrothiazol-2-ylthio)-4H-1,2,4-triazol-3-ol
• 4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-((5-nitro-thiazol-2-yl)thio)-1H-1,2,4-triazol-5(4H)-
• BI-78D3 >=98% (HPLC)
• JNK Inhibitor X, BI-78D3 - CAS 883065-90-5 - Calbiochem
• 4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-((5-nitro-thiazol-2-yl)thio)-1H-1,2,4-triazol-5(4H)-one
• 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[(5-nitro-2-thiazolyl)thio]-1H-1,2,4-triazol-5-one
• BI 78D3

BI-78D3

CAS: 883065-90-5

Formula: C₁₃H₉N₅O₅S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 379.3711

Ref: IN-DA008A6T

BI-78D3

CAS: 883065-90-5

BI-78D3

Purity: ≥95%

Molecular weight: 379.37g/mol

Ref: 54-BUP10067

BI-78D3

CAS: 883065-90-5

BI-78D3

Formula: C₁₃H₉N₅O₅S₂

Purity: 99.9% (Typical Value in Batch COA)

Color and Shape: yellow solid

Molecular weight: 379.37g/mol

Ref: 54-BISN0178

BI-78D3

CAS: 883065-90-5

BI-78D3, a competitive JNK inhibitor. IC50 of BI-78D3 is 280 nM that displays > 100 fold selectivity over p38α, and have no activity at mTOR and PI-3K.

Formula: C₁₃H₉N₅O₅S₂

Purity: 97.89% - >99.99%

Color and Shape: Solid

Molecular weight: 379.37

Ref: TM-T6784

4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-((5-nitrothiazol-2-yl)thio)-1H-1,2,4-triazol-5(4H)-one

CAS: 883065-90-5

Formula: C₁₃H₉N₅O₅S₂

Purity: 98%

Molecular weight: 379.37

Ref: 10-F232418