CAS 88343-72-0

2-Chloroethyl 1-(methylsulfonyl)methanesulfonate

Description:

2-Chloroethyl 1-(methylsulfonyl)methanesulfonate, with the CAS number 88343-72-0, is a chemical compound characterized by its sulfonate functional groups and a chloroethyl moiety. It is typically a colorless to pale yellow liquid, exhibiting a moderate level of solubility in polar solvents such as water and alcohols, due to the presence of sulfonate groups. This compound is known for its reactivity, particularly in nucleophilic substitution reactions, making it useful in organic synthesis and as an intermediate in the production of various pharmaceuticals and agrochemicals. Its structure includes a chloroethyl group, which can act as a leaving group, facilitating further chemical transformations. Additionally, the presence of methylsulfonyl groups contributes to its polar nature and potential biological activity. Safety precautions are essential when handling this compound, as it may pose health risks, including irritation to skin and eyes, and potential toxicity. Proper storage and disposal methods should be followed to mitigate environmental impact.

Formula: C₄H₉ClO₅S₂

InChI: InChI=1/C4H9ClO5S2/c1-11(6,7)4-12(8,9)10-3-2-5/h2-4H2,1H3

InChI key: InChIKey=SEHSPJCWCBQHPF-UHFFFAOYSA-N

SMILES: C(S(OCCCl)(=O)=O)S(C)(=O)=O

Synonyms:

• 2-Chloroethyl 1-(methylsulfonyl)methanesulfonate
• 2-Chloroethyl methanesulfonylmethanesulfonate
• 2-Chloroethyl methylsulfonylmethanesulfonate
• Chlorethyl SOSO
• Clomesone
• Methanesulfonic Acid, 1-(Methylsulfonyl)-, 2-Chloroethyl Ester
• Methanesulfonic acid, (methylsulfonyl)-, 2-chloroethyl ester
• NSC 338947
• 2-Chloroethyl (methylsulfonyl)methanesulfonate
• (Methylsulfonyl)methanesulfonic acid 2-chloroethyl ester
• SRI-6155

Clomesone

CAS: 88343-72-0

Clomesone

Purity: ≥98%

Molecular weight: 236.69g/mol

Ref: 54-BUP08439

Clomesone

CAS: 88343-72-0

Clomesone, a synthetic drug, treats female infertility by blocking brain estrogen, inducing ovulation.

Formula: C₄H₉ClO₅S₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 236.69

Ref: TM-T50086

2-Chloroethyl methanesulfonylmethanesulfonate

CAS: 88343-72-0

2-Chloroethyl methanesulfonylmethanesulfonate (2CEMS) is a potent and selective inhibitor of the enzyme methyltransferase. This drug has been shown to be effective against leukemic mice, as well as against carcinoma cell lines in vitro. 2CEMS is also active in vivo, inhibiting the growth of bladder tumours in rats. The mechanism of action is not fully understood but may involve carbamoylation, which inhibits the production of fatty acids and nucleic acids. 2-Chloroethyl methanesulfonylmethanesulfonate has been shown to enhance antitumour activity when used in combination with specific antibodies.

Formula: C₄H₉ClO₅S₂

Purity: Min. 95%

Molecular weight: 236.7 g/mol

Ref: 3D-NDA34372