CAS 88373-73-3

enkephalin

Description:

Enkephalins are a group of endogenous peptides that function as neurotransmitters and are part of the body's natural pain control system. They are classified as opioid peptides, which means they bind to opioid receptors in the brain, modulating pain perception and emotional responses. Enkephalins are composed of five amino acids, typically featuring the sequences Tyr-Gly-Gly-Phe-Leu or Tyr-Gly-Gly-Phe-Met, depending on the specific type (leucine enkephalin or methionine enkephalin). They are produced in various regions of the central nervous system and are involved in regulating pain, stress, and immune responses. Enkephalins exhibit a high affinity for the delta and mu opioid receptors, contributing to their analgesic effects. The CAS number 88373-73-3 specifically identifies a synthetic form of enkephalin, which may be used in research and therapeutic applications. Overall, enkephalins play a crucial role in neurobiology and pharmacology, influencing both physiological and psychological processes.

Formula: C₃₀H₃₉N₅O₇S₂

InChI: InChI=1/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1

SMILES: CC1(C)[C@H](C(=NCC(=N[C@@H](Cc2ccccc2)C(=N[C@@H](C(=O)O)C(C)(C)SS1)O)O)O)N=C([C@H](Cc1ccc(cc1)O)N)O

Synonyms:

• (D-pen 2,5)-enkephalin
• (D-Pen2,D-Pen5)-Enkephalin
• H-Tyr-D-Pen-Gly-Phe-D-Pen-OH (Disulfide bond)
• (4S,7S,13S)-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-13-(L-tyrosylamino)-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid
• Dpdpe

(D-Pen²,D-Pen⁵)-Enkephalin

CAS: 88373-73-3

DPDPE mediates its direct antinociceptive actions via the δ₁-opioid receptor while its modulatory effects are mediated via the δ₂-opioid receptor.

Formula: C₃₀H₃₉N₅O₇S₂

Purity: 99.5%

Color and Shape: White Powder

Molecular weight: 645.8

Ref: 01-4008254

DPDPE

CAS: 88373-73-3

DPDPE is selective δ-opioid receptor agonist peptide.

Formula: C₃₀H₃₉N₅O₇S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 645.79

Ref: TM-TP2036

DPDPE

CAS: 88373-73-3

δ-opioid receptor agonist; anti-nociceptive; anti-convulsant

Formula: C₃₀H₃₉N₅O₇S₂

Purity: Min. 95%

Molecular weight: 645.79 g/mol

Ref: 3D-BP108798