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CAS 88416-60-8

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2-[p-(Hydroxymethyl)phenyl]propionic acid

Description:
2-[p-(Hydroxymethyl)phenyl]propionic acid, commonly known as ibuprofen, is a nonsteroidal anti-inflammatory drug (NSAID) widely used for its analgesic, antipyretic, and anti-inflammatory properties. It is characterized by its propionic acid structure, which includes a phenyl ring substituted with a hydroxymethyl group at the para position. This compound is typically a white to off-white crystalline powder that is slightly soluble in water but more soluble in organic solvents. Its mechanism of action involves the inhibition of cyclooxygenase (COX) enzymes, leading to a decrease in the synthesis of prostaglandins, which are mediators of inflammation and pain. Ibuprofen is commonly used to relieve mild to moderate pain, reduce fever, and alleviate inflammation associated with various conditions, including arthritis and menstrual cramps. Due to its widespread use, it is important to consider potential side effects, such as gastrointestinal discomfort and cardiovascular risks, particularly with long-term use or in high doses.
Formula:C10H12O3
Synonyms:
  • 2-[p-(Hydroxymethyl)phenyl]propionic acid,Loxoprofen impurity 10
  • 2-[4-(Hydroxymethyl)phenyl]propionic acid
  • 2-(4-(hydroxymethyl)phenyl)propanoic acid
  • 2-[p-(Hydroxymethyl)phenyl]propionic acid
  • Benzeneacetic acid, 4-(hydroxymethyl)-α-methyl-
  • Loxoprofen impurity 1/2-(4-(hydroxymethyl)phenyl)propanoic acid
  • Loxoprofen Impurity 57
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