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CAS 88426-32-8

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Ursulcholic acid

Description:
Ursodeoxycholic acid, often referred to as ursulcholic acid, is a bile acid that is primarily derived from the bile of bears and is also found in smaller amounts in human bile. It is classified as a hydrophilic bile acid, which distinguishes it from other bile acids that are more hydrophobic. Ursodeoxycholic acid is known for its ability to reduce cholesterol absorption and promote the dissolution of cholesterol gallstones. Its chemical structure features a steroid backbone with hydroxyl groups that enhance its solubility in water. This compound exhibits various biological activities, including cytoprotective effects on liver cells and potential therapeutic applications in treating liver diseases, such as primary biliary cholangitis and certain types of cholestasis. Additionally, it has been studied for its immunomodulatory properties. Ursodeoxycholic acid is generally well-tolerated, with a favorable safety profile, making it a valuable agent in clinical settings for managing specific gastrointestinal and liver disorders.
Formula:C24H40O10S2
InChI:InChI=1/C24H40O10S2/c1-14(4-7-21(25)26)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(33-35(27,28)29)12-15(23)13-20(22)34-36(30,31)32/h14-20,22H,4-13H2,1-3H3,(H,25,26)(H,27,28,29)(H,30,31,32)/t14-,15+,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1
Synonyms:
  • (3alpha,5beta,7beta)-3,7-bis(sulfooxy)cholan-24-oic acid
  • Ursulcholic acid [INN]
  • UNII-AJS8W2AXJH
  • 3alpha,7beta-Dihydroxy-5beta-cholan-24-oic acid bis(hydrogen sulfate)
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