CAS 88430-50-6
:Beraprost
Description:
Beraprost is a synthetic compound classified as a prostacyclin analog, primarily used for its vasodilatory effects. It is known for its ability to mimic the action of prostacyclin (PGI2), a naturally occurring compound that plays a crucial role in vascular biology by promoting vasodilation and inhibiting platelet aggregation. Beraprost is often utilized in the treatment of conditions such as pulmonary arterial hypertension and peripheral vascular diseases. The substance is characterized by its relatively low molecular weight and specific structural features that enhance its stability and bioavailability compared to natural prostacyclin. Beraprost is administered orally and has been shown to improve exercise capacity and overall quality of life in patients with vascular disorders. Its pharmacological profile includes a rapid onset of action, although the duration of effect may vary. As with any medication, potential side effects can include headache, flushing, and gastrointestinal disturbances, necessitating careful monitoring during treatment.
Formula:C24H30O5
InChI:InChI=1/C24H30O5/c1-3-4-7-15(2)19(25)13-12-17-20(26)14-21-23(17)18-10-5-8-16(24(18)29-21)9-6-11-22(27)28/h5,8,10,12-13,15,17,19-21,23,25-26H,6-7,9,11,14H2,1-2H3,(H,27,28)/b13-12+/t15?,17-,19+,20+,21-,23-/m0/s1
InChI key:InChIKey=CTPOHARTNNSRSR-UHFFFAOYSA-N
SMILES:C(=CC(C(CC#CC)C)O)C1C2C=3C(OC2CC1O)=C(CCCC(O)=O)C=CC3
Synonyms:- 1H-Cyclopenta[b]benzofuran-5-butanoic acid, 2,3,3a,8b-tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-yn-1-yl)-
- 1H-Cyclopenta[b]benzofuran-5-butanoic acid, 2,3,3a,8b-tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-ynyl)-
- 2,3,3a,8b-Tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-yn-1-yl)-1H-cyclopenta[b]benzofuran-5-butanoic acid
- 4-{(1R,2R,3aS,8bS)-2-hydroxy-1-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan-5-yl}butanoic acid
- 4-{2-hydroxy-1-[(1E)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan-5-yl}butanoic acid
- Mdl 201229
- Ml 1229
- Beraprost
- Beraprostum [inn-latin]
- 2,3,3α,8b-Tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-ynyl)-1H-cyclopenta[b]benzofuran-5-butanoic acid
- Beraprostum
- 2,3,3a,8b-Tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-ynyl)-1H-cyclopenta[b]benzofuran-5-butanoic acid
- 88475-69-8 (Hydrochloride salt)
- 2-Hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2,3,3A,8B-tetrahydro-1H-cyclopenta(B)benzofuran-5-butanoic acid
- Unii-35E3njj4o6
- Befaprost
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Found 3 products.
Beraprost
CAS:Beraprost is a stable prostacyclin analog.Formula:C24H30O5Color and Shape:SolidMolecular weight:398.49Beraprost-d3
CAS:Controlled Product<p>Applications Labelled Beraprost. Platelet aggregation inhibitor; stable analog of Prostacyclin. Antithrombotic; vasodilator (peripheral).<br>References Kajikawa, N., et al.: Arzneim.-Forsch., 39, 495 (1989), Demolis, J.-L., et al.: J. Cardiovasc. Pharmacol., 22, 711 (1993), Okuda, Y., et al.: Prostaglandins, 52, 375 (1996),<br></p>Formula:C24D3H27O5Color and Shape:NeatMolecular weight:401.51


