CAS 88467-44-1

N-succinyl-ala-pro-ala 7-amido-4-*methylcoumarin

Description:

N-succinyl-ala-pro-ala 7-amido-4-methylcoumarin is a synthetic compound often utilized in biochemical research, particularly in the study of proteolytic enzymes. This substance features a coumarin moiety, which is known for its fluorescent properties, making it useful as a substrate in enzyme assays. The presence of the succinyl group enhances its solubility and stability in aqueous solutions, while the amino acid sequence (alanine-proline-alanine) contributes to its specificity as a substrate for certain proteases. The compound is typically characterized by its ability to undergo hydrolysis, releasing the fluorescent coumarin upon cleavage by target enzymes. This property allows for the monitoring of enzyme activity in real-time, providing valuable insights into enzyme kinetics and mechanisms. Additionally, the compound's structure may influence its interaction with biological systems, making it a useful tool in drug discovery and development. Safety data sheets should be consulted for handling and storage guidelines, as with any chemical substance.

Formula: C₂₅H₃₀N₄O₈

Synonyms:

• Suc-Ala-Pro-Ala-AMC

Suc-Ala-Pro-Ala-AMC

CAS: 88467-44-1

Suc-APA-AMC, a sensitive substrate for human neutrophil elastase.

Formula: C₂₅H₃₀N₄O₈

Purity: ≥ 98%

Color and Shape: White

Molecular weight: 514.54

Ref: 01-4005965

Suc-Ala-Pro-Ala-AMC

CAS: 88467-44-1

Suc-Ala-Pro-Ala-AMC is a synthetic peptide that is used as a research tool in pharmacology, cell biology, and other life science fields. This peptide is an activator of ion channels, which are proteins that allow the flow of ions across cell membranes. Suc-Ala-Pro-Ala-AMC binds to ligand receptors on the surface of cells and activates them by opening the channel. The high purity of this product makes it suitable for use in research applications where specific binding is required.

Formula: C₂₅H₃₀N₄O₈

Purity: Min. 95%

Molecular weight: 514.53 g/mol

Ref: 3D-MAP-3100-V

Suc-Ala-Pro-Ala-AMC

CAS: 88467-44-1

Suc-Ala-Pro-Ala-AMC is a synthetic peptide that is used as a fluorescent substrate to measure the activity of serine proteases. It is used in plant physiology and has been shown to be effective in the treatment of inflammatory diseases. Suc-Ala-Pro-Ala-AMC is an acidic molecule with a pKa of 3.1. This means it can exist as both a zwitterion, with a positive charge on one end and negative charge on the other, or as an ionized molecule with both ends having a negative charge. The zwitterionic form is more stable than the ionized form at low pH levels and will therefore be present at higher concentrations at lower pH values. Suc-Ala-Pro-Ala-AMC shows proteolytic activity against peptidases such as papain, bromelain, trypsin, and chymotrypsin. It also binds to neutroph

Formula: C₂₅H₃₀N₄O₈

Purity: Min. 95%

Molecular weight: 514.53 g/mol

Ref: 3D-FS110523