CAS 88467-45-2

N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-{(2S)-2-[(4-methyl-2-oxo-2H-chromen-7-yl)amino]-3-phenylpropanoyl}-L-prolinamide

Description:

N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-{(2S)-2-[(4-methyl-2-oxo-2H-chromen-7-yl)amino]-3-phenylpropanoyl}-L-prolinamide, with CAS number 88467-45-2, is a complex organic compound characterized by its multi-functional structure, which includes amino acid residues and a chromenyl moiety. This compound features a carboxylic acid group, contributing to its potential as a bioactive molecule. The presence of multiple chiral centers indicates that it may exhibit stereochemical diversity, which can influence its biological activity and interactions. The chromenyl group suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to its ability to interact with biological targets. Additionally, the compound's amide linkages may enhance its stability and solubility in biological systems. Overall, this substance represents a class of compounds that could be of interest in drug design and development, particularly in the context of targeting specific biological pathways or receptors.

Formula: C₃₄H₃₉N₅O₉

InChI: InChI=1/C34H39N5O9/c1-19-16-30(43)48-27-18-23(11-12-24(19)27)37-25(17-22-8-5-4-6-9-22)32(45)38-33(46)26-10-7-15-39(26)34(47)21(3)36-31(44)20(2)35-28(40)13-14-29(41)42/h4-6,8-9,11-12,16,18,20-21,25-26,37H,7,10,13-15,17H2,1-3H3,(H,35,40)(H,36,44)(H,41,42)(H,38,45,46)/t20-,21-,25-,26-/m0/s1

SMILES: Cc1cc(=O)oc2cc(ccc12)N[C@@H](Cc1ccccc1)C(=NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)N=C([C@H](C)N=C(CCC(=O)O)O)O)O

Synonyms:

• Factor Xiia Substrate Dihydrochloride

Suc-Ala-Ala-Pro-Phe-AMC

CAS: 88467-45-2

The peptidylprolyl isomerase substrate Suc-AAPF-AMC is also hydrolyzed by carboxypeptidase Y, cathepsin G, and chymotrypsin. Suc-AAPF-AMC has also been used to analyze the chymotrypsin-like activity of trypsins.

Formula: C₃₄H₃₉N₅O₉

Purity: 99.5%

Color and Shape: White

Molecular weight: 661.71

Ref: 01-4012873

Suc-Ala-Ala-Pro-Phe-AMC

CAS: 88467-45-2

Suc-Ala-Ala-Pro-Phe-AMC is a synthetic substrate for proteolytic enzymes. This substrate has been shown to be hydrolyzed by pancreatic trypsin and soybean trypsin with similar rates. Suc-Ala-Ala-Pro-Phe-AMC is also a substrate for erythrocyte eosinophil peroxidase, which has been shown to have an optimum pH of 5.0. The reaction mechanism of this substrate is not yet fully understood, but it may involve the formation of a Schiff base between the amino group on the proline residue and the carbonyl group on the AMC moiety. Suc-Ala-Ala-Pro-Phe-AMC also reacts with surface membranes and can be used as an indicator of protease activity.

Formula: C₃₄H₃₉N₅O₉

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 661.7 g/mol

Ref: 3D-FS48217

Suc-Ala-Ala-Pro-Phe-AMC

CAS: 88467-45-2

Suc-Ala-Ala-Pro-Phe-AMC is a peptide that is an activator of the acetylcholine receptor. Suc-Ala-Ala-Pro-Phe-AMC has been shown to inhibit the binding of the ligand to the receptor and also prevent activation of ion channels. It has been used as a research tool for studying protein interactions, as well as, antibody production and cell biology. This peptide can also be used as a pharmacological agent, which may be useful in treating diseases such as Alzheimer's disease.

Formula: C₃₄H₃₉N₅O₉

Purity: Min. 95%

Molecular weight: 661.7 g/mol

Ref: 3D-MAA-3114-V