CAS 88497-87-4

(αR,α′R)-α,α′-[[(2S,3R,4R,5S)-Tetrahydro-3,4-dimethyl-2,5-furandiyl]bis[(2-methoxy-4,1-phenylene)oxy-(1R)-ethylidene]]bis[3,4-dimethoxybenzenemethanol]

Description:

The chemical substance with the name "(αR,α′R)-α,α′-[[[2S,3R,4R,5S)-Tetrahydro-3,4-dimethyl-2,5-furandiyl]bis[(2-methoxy-4,1-phenylene)oxy-(1R)-ethylidene]]bis[3,4-dimethoxybenzenemethanol]" and CAS number "88497-87-4" is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups and stereocenters. This compound features a furan moiety, indicating potential reactivity and interactions typical of furan derivatives. The presence of methoxy and phenyl groups suggests that it may exhibit interesting electronic properties and solubility characteristics. Additionally, the stereochemistry denoted by the (αR,α′R) configuration implies that the compound may have specific spatial arrangements that could influence its biological activity or reactivity. Such compounds are often investigated for their potential applications in pharmaceuticals, materials science, or as intermediates in organic synthesis. However, detailed studies would be necessary to fully understand its properties, including solubility, stability, and reactivity under various conditions.

Formula: C₄₂H₅₂O₁₁

InChI: InChI=1S/C42H52O11/c1-23-24(2)42(30-14-18-34(38(22-30)50-10)52-26(4)40(44)28-12-16-32(46-6)36(20-28)48-8)53-41(23)29-13-17-33(37(21-29)49-9)51-25(3)39(43)27-11-15-31(45-5)35(19-27)47-7/h11-26,39-44H,1-10H3/t23-,24-,25-,26-,39+,40+,41+,42+/m1/s1

InChI key: InChIKey=ZGXXNVOBEIRACL-VOGCUZRYSA-N

SMILES: C[C@H]1[C@H](O[C@@H]([C@@H]1C)C2=CC(OC)=C(O[C@@H]([C@H](O)C3=CC(OC)=C(OC)C=C3)C)C=C2)C4=CC(OC)=C(O[C@@H]([C@H](O)C5=CC(OC)=C(OC)C=C5)C)C=C4

Synonyms:

• (-)-ManassantinA
• (αR,α′R)-α,α′-[[(2S,3R,4R,5S)-Tetrahydro-3,4-dimethyl-2,5-furandiyl]bis[(2-methoxy-4,1-phenylene)oxy-(1R)-ethylidene]]bis[3,4-dimethoxybenzenemethanol]
• Benzenemethanol, α,α′-[[(2S,3R,4R,5S)-tetrahydro-3,4-dimethyl-2,5-furandiyl]bis[(2-methoxy-4,1-phenylene)oxy-(1R)-ethylidene]]bis[3,4-dimethoxy-, (αR,α′R)-
• Hnp 98701C
• Manassantin A
• Saucernetin A
• Manassantin A-RM
• Benzenemethanol, α,α'-[[(2S,3R,4R,5S)-tetrahydro-3,4-dimethyl-2,5-furandiyl]bis[(2-methoxy-4,1-phenylene)oxy-(1R)-ethylidene]]bis[3,4-dimethoxy-, (αR,α'R)-
• (-)-α,α'-[(Tetrahydro-3,4-dimethyl-2,5-furandiyl)bis[(2-methoxy-4,1-phenylene)oxyethane-1,1-diyl]]bis[3,4-dimethoxybenzenemethanol]

Manassantin A

CAS: 88497-87-4

Manassantin A: potent HIF-1 inhibitor, guards stomach lining, curbs iNOS/NF-κB, may help treat airway diseases, reduces melanin by affecting MITF/tyrosinase.

Formula: C₄₂H₅₂O₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 732.87

Ref: TM-TN4489

Manassantin A

CAS: 88497-87-4

Formula: C₄₂H₅₂O₁₁

Purity: 95%~99%

Molecular weight: 732.867

Ref: BP-BP0920

Manassantin a

CAS: 88497-87-4

Compound with non-condensed furan ring

Formula: C₄₂H₅₂O₁₁

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 732.87

Ref: 5G-83243

Manassantin A

Controlled Product

CAS: 88497-87-4

Formula: C₄₂H₅₂O₁₁

Color and Shape: Neat

Molecular weight: 732.856

Ref: TR-M162005

Manassantin A

CAS: 88497-87-4

Manassantin A is a type of natural product that has potent antitumor activity. It causes apoptosis in HL-60 cells, which may be due to its ability to cause the release of cytochrome c from the mitochondria into the cytosol and subsequent activation of caspase-3. Manassantin A also increases mitochondrial membrane potential by inhibiting ATP synthesis and reducing levels of ATP. The extract can also reduce levels of epidermal growth factor and protein target, thereby blocking tumor growth. Manassantin A is derived from an acetate extract of the plant Chinensis, which contains manassantin, a type of natural product that has been shown to inhibit tumor growth in mice.

Formula: C₄₂H₅₂O₁₁

Purity: Min. 95%

Molecular weight: 732.9 g/mol

Ref: 3D-NDA49787