CAS 885060-08-2

1,3,4-Thiadiazole-3(2H)-carboxamide,2-(3-aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-, (2R)-

Description:

1,3,4-Thiadiazole-3(2H)-carboxamide, 2-(3-aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-, (2R)- is a complex organic compound characterized by its thiadiazole ring, which contributes to its potential biological activity. The presence of a carboxamide functional group enhances its solubility and reactivity, while the difluorophenyl and phenyl substituents may influence its pharmacological properties. The compound also features a propylamine side chain, which can affect its interaction with biological targets. Its stereochemistry, indicated by the (2R) designation, suggests specific spatial arrangements that may be crucial for its activity. This compound is likely to exhibit properties such as moderate to high lipophilicity due to the aromatic rings, which can facilitate membrane permeability. Additionally, the presence of fluorine atoms may enhance metabolic stability and alter the electronic properties of the molecule. Overall, this compound's unique structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting various biological pathways.

Formula: C₂₀H₂₂F₂N₄O₂S

(R)-Filanesib

CAS: 885060-08-2

(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).

Formula: C₂₀H₂₂F₂N₄O₂S

Color and Shape: Solid

Molecular weight: 420.48

Ref: TM-T10373