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CAS 88509-92-6

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9α-Hydroxymatrine

Description:
9α-Hydroxymatrine is a chemical compound derived from matrine, which is an alkaloid extracted from the Sophora species, particularly Sophora flavescens. This compound is characterized by its hydroxyl group at the 9α position, which influences its biological activity. It typically appears as a white to off-white crystalline powder and is soluble in organic solvents. 9α-Hydroxymatrine has garnered interest in pharmacological research due to its potential therapeutic effects, including anti-inflammatory, anti-tumor, and hepatoprotective properties. Its mechanism of action may involve modulation of various signaling pathways and inhibition of specific enzymes. Additionally, studies have indicated that it may exhibit antimicrobial activity. As with many alkaloids, the safety profile and potential side effects of 9α-Hydroxymatrine are important considerations for its use in medicinal applications. Ongoing research aims to further elucidate its pharmacokinetics, efficacy, and potential applications in treating various diseases.
Formula:C15H24N2O2
InChI:InChI=1S/C15H24N2O2/c18-11-7-12-13-4-1-5-14(19)17(13)8-10-3-2-6-16(9-11)15(10)12/h10-13,15,18H,1-9H2/t10-,11-,12+,13+,15-/m0/s1
InChI key:InChIKey=JTWPUVIWKODBID-WHPHWUKISA-N
SMILES:O[C@H]1C[C@]2([C@@]3([C@](CN4[C@@]2(CCCC4=O)[H])(CCCN3C1)[H])[H])[H]
Synonyms:
  • Matridin-15-one, 9-hydroxy-, (9α)-
  • (2S,7aS,13aR,13bR,13cS)-Dodecahydro-2-hydroxy-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one
  • 9α-Hydroxymatrine
  • 1H,5H,10H-Dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one, dodecahydro-2-hydroxy-, (2S,7aS,13aR,13bR,13cS)-
  • 1H,5H,8H-Dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridine, matridin-15-one deriv.
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