CAS 885101-89-3

3-{4-[(3-Phenoxybenzyl)amino]phenyl}propanoic acid

Description:

3-{4-[(3-Phenoxybenzyl)amino]phenyl}propanoic acid, with the CAS number 885101-89-3, is an organic compound characterized by its complex structure, which includes a propanoic acid moiety linked to a phenyl group that is further substituted with a phenoxybenzylamino group. This compound typically exhibits properties associated with both aromatic and aliphatic systems, contributing to its potential biological activity. It is likely to be soluble in organic solvents due to its aromatic components, while the carboxylic acid group may impart some degree of polarity, allowing for solubility in polar solvents as well. The presence of multiple functional groups suggests that it may engage in various chemical interactions, making it of interest in medicinal chemistry and drug design. Additionally, its structural features may influence its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion (ADME), which are critical for evaluating its potential therapeutic applications.

Formula: C₂₂H₂₁NO₃

InChI: InChI=1/C22H21NO3/c24-22(25)14-11-17-9-12-19(13-10-17)23-16-18-5-4-8-21(15-18)26-20-6-2-1-3-7-20/h1-10,12-13,15,23H,11,14,16H2,(H,24,25)

InChI key: DGENZVKCTGIDRZ-UHFFFAOYSA-N

SMILES: c1ccc(cc1)Oc1cccc(c1)CNc1ccc(cc1)CCC(=O)O

Synonyms:

• Benzenepropanoic acid, 4-[[(3-phenoxyphenyl)methyl]amino]-
• Gw9508

GW9508

CAS: 885101-89-3

GW9508

Formula: C₂₂H₂₁NO₃

Purity: ≥95%

Molecular weight: 347.41

Ref: 54-BUP11336

GW9508

CAS: 885101-89-3

Formula: C₂₂H₂₁NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 347.4070

Ref: IN-DA0049CW

3-(4-{[(3-Phenoxyphenyl)methyl]amino}phenyl)propanoic acid

CAS: 885101-89-3

3-(4-{[(3-Phenoxyphenyl)methyl]amino}phenyl)propanoic acid

Formula: C₂₂H₂₁NO₃

Purity: 98%

Molecular weight: 347.40704

Ref: 54-OR1021345

GW9508

CAS: 885101-89-3

3-(4-((3-Phenoxybenzyl)amino)phenyl)propanoic acid

Formula: C₂₂H₂₁NO₃

Purity: 98%

Molecular weight: 347.41

Ref: IN-DG208187

GW9508

CAS: 885101-89-3

GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.

Formula: C₂₂H₂₁NO₃

Purity: 97.89% - 99.19%

Color and Shape: White Solid

Molecular weight: 347.41

Ref: TM-T1781

3-(4-((3-Phenoxybenzyl)amino)phenyl)propanoic acid

CAS: 885101-89-3

Formula: C₂₂H₂₁NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 347.414

Ref: 10-F221962

GW9508

Controlled Product

CAS: 885101-89-3

Applications GW9508 is a GPR40 full agonist, used to regulate glucose in rats. Can be applied to the treatment of diabetes type 2. GPR120 selective and potent agonist also used in the treatment of diabetes type 2 due to GPR120’s ability to mediate GLP-1 secretion, insulin sensitization and anti-obesity effects.
References Luo, J. et al.: PLoS One., 7, 46300 (2012); Shimpukade, B. et al.: J. Med. Chem., 55, 4511 (2012);

Formula: C₂₂H₂₁NO₃

Color and Shape: Neat

Molecular weight: 347.41

Ref: TR-G931250

GPR40 Agonist

CAS: 885101-89-3

GW9508 is a GPR40 agonist that activates the receptor and increases cytosolic calcium. It has been shown to increase glucose uptake in pluripotent cells and decrease glucose production by decreasing the activity of gluconeogenic enzymes. GW9508 is also a potential drug for diabetes as it can stimulate insulin secretion. This drug has been shown to activate toll-like receptors, which are proteins that sense microbial infections and regulate inflammatory responses. It may also act as an agonist for other receptors such as DPP-IV inhibitors or response elements.

Formula: C₂₂H₂₁NO₃

Purity: Min. 95%

Molecular weight: 347.41 g/mol

Ref: 3D-KKB10189