CAS 885104-09-6

LY 2389575 hydrochloride

CAS: 885104-09-6

LY2389575 hydrochloride is a selective mGlu3 NAM with 190 nM IC50, increases Mrc1, and aids Alzheimer's research.

Formula: C₁₅H₁₆BrCl₃N₄

Purity: 99.45%

Color and Shape: Solid

Molecular weight: 438.58

Ref: TM-T22204

(3S)-N-(2,4-Dichlorobenzyl)-1-(5-bromopyrimidin-2-yl)pyrrolidinyl-3-aminehydrochloride

CAS: 885104-09-6

Formula: C₁₅H₁₆BrCl₃N₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 438.5773

Ref: IN-DA01ENNB

LY 2389575 hydrochloride

CAS: 885104-09-6

LY 2389575 hydrochloride

Purity: ≥98%

Molecular weight: 438.58g/mol

Ref: 54-BUP03731

Ly 2389575 hydrochloride

CAS: 885104-09-6

Ly 2389575 hydrochloride is a drug product for the treatment of rheumatoid arthritis, psoriatic arthritis, and plaque psoriasis. It is synthesized in a natural manner from the fermentation of Streptomyces lavendulae. The compound has been shown to be metabolized through a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Ly 2389575 hydrochloride also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Formula: C₁₅H₁₆BrCl₃N₄

Purity: Min. 95%

Molecular weight: 438.6 g/mol

Ref: 3D-KKB10409