CAS 885126-40-9

Benzamide,N-methyl-2-[[3-[(1Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-

Description:

Benzamide, N-methyl-2-[[3-[(1Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]- is a chemical compound characterized by its complex structure, which includes a benzamide moiety and a thioether linkage. The presence of a pyridine ring and an indazole structure contributes to its potential biological activity. This compound is likely to exhibit properties typical of amides, such as moderate solubility in polar solvents and stability under standard conditions. The thioether group may enhance its reactivity and influence its interaction with biological targets. Given its structural components, it may be of interest in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific pathways or receptors. The compound's CAS number, 885126-40-9, allows for precise identification and retrieval of information in chemical databases. Overall, the characteristics of this compound suggest potential applications in research and development, particularly in the fields of drug discovery and chemical biology.

Formula: C₂₂H₁₈N₄OS

Axitinib Impurity 1

CAS: 885126-40-9

Formula: C₂₂H₁₈N₄OS

Color and Shape: Yellow Solid

Molecular weight: 386.47

Ref: 4Z-A-188002

N-Methyl-2-[[3-[(1Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide

Controlled Product

CAS: 885126-40-9

Applications N-Methyl-2-[[3-[(1Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide is an impurity of Axitinib (A794650), a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),

Formula: C₂₂H₁₈N₄OS

Color and Shape: Neat

Molecular weight: 386.4695

Ref: TR-M338913

Cis-axitinib

CAS: 885126-40-9

Formula: C₂₂H₁₈N₄OS

Molecular weight: 386.47

Ref: ST-EA-CP-A34012