CAS 885220-61-1

Verucerfont

Description:

Verucerfont, identified by its CAS number 885220-61-1, is a selective antagonist of the corticotropin-releasing factor (CRF) receptor 1. This compound is primarily investigated for its potential therapeutic applications in treating anxiety and stress-related disorders. Verucerfont exhibits a high affinity for the CRF receptor, which plays a crucial role in the body’s response to stress. Its mechanism of action involves blocking the effects of CRF, thereby modulating the hypothalamic-pituitary-adrenal (HPA) axis and reducing anxiety-related behaviors. In terms of physical and chemical properties, Verucerfont is characterized by its specific molecular structure, which contributes to its biological activity. The compound is typically studied in preclinical and clinical settings to evaluate its efficacy, safety, and pharmacokinetic profile. As research continues, Verucerfont may offer insights into novel treatment strategies for conditions linked to dysregulation of the stress response system.

Formula: C₂₂H₂₆N₆O₂

InChI: InChI=1S/C22H26N6O2/c1-7-18(22-24-15(5)27-30-22)25-19-11-13(3)23-21-20(14(4)26-28(19)21)17-9-8-16(29-6)10-12(17)2/h8-11,18,25H,7H2,1-6H3/t18-/m0/s1

InChI key: InChIKey=VKHVAUKFLBBZFJ-SFHVURJKSA-N

SMILES: CC=1C(=C2N(C(N[C@@H](CC)C=3ON=C(C)N3)=CC(C)=N2)N1)C4=C(C)C=C(OC)C=C4

Synonyms:

• Verucerfont
• Pyrazolo[1,5-a]pyrimidin-7-amine, 3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]-
• NBI 77860
• 3-(4-Methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine
• GSK 561679A

Verucerfont

CAS: 885220-61-1

Verucerfont

Purity: ≥98%

Molecular weight: 406.48g/mol

Ref: 54-BUP03650

Verucerfont

CAS: 885220-61-1

Verucerfont (NBI77860) is an antagonist of corticotropin-releasing factor receptor 1 (CRF1) .

Formula: C₂₂H₂₆N₆O₂

Purity: 99.90%

Color and Shape: Solid

Molecular weight: 406.48

Ref: TM-T7361