CAS 88546-74-1: H-D-Pro-Phe-Arg-chloromethylketone
CAS 88546-74-1: H-D-Pro-Phe-Arg-chloromethylketone
Description:H-D-Pro-Phe-Arg-chloromethylketone, with the CAS number 88546-74-1, is a synthetic peptide derivative that serves as a potent inhibitor of certain proteolytic enzymes, particularly serine proteases. This compound is characterized by its unique structure, which includes a chloromethylketone moiety that is crucial for its inhibitory activity. The presence of the amino acid residues D-Proline (D-Pro), Phenylalanine (Phe), and Arginine (Arg) contributes to its specificity and binding affinity for target enzymes. Typically, such compounds are utilized in biochemical research to study enzyme mechanisms and to develop therapeutic agents. The chloromethylketone functionality allows for covalent modification of the active site of serine proteases, effectively blocking their activity. As a peptide derivative, it may exhibit properties such as solubility in polar solvents and potential bioactivity, making it of interest in pharmacological studies. However, handling and usage require caution due to its reactive nature and potential toxicity.
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