CAS 88574-06-5

N-Fmoc-6-aminohexanoic acid

Description:

N-Fmoc-6-aminohexanoic acid is a derivative of aminohexanoic acid, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protective group attached to the amino group. This compound is typically utilized in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), due to the stability of the Fmoc group under basic conditions and its ease of removal under mild acidic conditions. The structure of N-Fmoc-6-aminohexanoic acid includes a six-carbon aliphatic chain, which contributes to its hydrophobic properties, making it useful for enhancing the solubility and stability of peptides. The presence of the amino group allows for further coupling reactions, facilitating the formation of peptide bonds. Additionally, the Fmoc group provides a means for selective protection, enabling the synthesis of complex peptides with multiple functional groups. Overall, N-Fmoc-6-aminohexanoic acid is a valuable building block in the field of peptide chemistry, offering versatility and efficiency in synthetic applications.

Formula: C₂₁H₂₃NO₄

InChI: InChI=1/C21H23NO4/c23-20(24)12-2-1-7-13-22-21(25)26-14-19-17-10-5-3-8-15(17)16-9-4-6-11-18(16)19/h3-6,8-11,19H,1-2,7,12-14H2,(H,22,25)(H,23,24)

SMILES: C(CCC(=O)O)CCN=C(O)OCC1c2ccccc2c2ccccc12

Synonyms:

• 6-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}hexanoic acid
• Hexanoic acid, 6-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-
• Fmoc-6-Aminohexanoic Acid
• Fmoc-e-Acp-OH

Fmoc-6-Ahx-OH

CAS: 88574-06-5

Formula: C₂₁H₂₃NO₄

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 353.42

Ref: 3B-F1319

6-(Fmoc-amino)hexanoic acid, 98%

CAS: 88574-06-5

6-(Fmoc-amino)hexanoic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refe

Formula: C₂₁H₂₃NO₄

Purity: 98%

Molecular weight: 353.42

Ref: 02-H63148

Fmoc-ε-aminocaproic acid

CAS: 88574-06-5

Protected flexible non-polar spacer moiety also abbreviated Fmoc-ε-Aca, Fmoc-ε-Ahx, or Fmoc-LC for use in Fmoc-SPPS. Bachem additionally offers Fmoc-εAhx-Wang resin (D-1050).

Formula: C₂₁H₂₃NO₄

Purity: 100.0%

Color and Shape: White Powder

Molecular weight: 353.42

Ref: 01-4006429

Fmoc-ε-Acp-OH

CAS: 88574-06-5

Formula: C₂₁H₂₃NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 353.4116

Ref: IN-DA003QMP

Fmoc-6-Ahx-OH

CAS: 88574-06-5

Formula: C₂₁H₂₃NO₄

Purity: ≥ 97.0% (anhydrous basis)

Color and Shape: White or almost white powder

Molecular weight: 353.41

Ref: 7W-GM0242

fmoc-E-acp-oh

CAS: 88574-06-5

Formula: C₂₁H₂₃NO₄

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 353.418

Ref: 10-F045380

Fmoc-6-Aca

CAS: 88574-06-5

Fmoc-6-Aca

Purity: 98%

Molecular weight: 353.41g/mol

Ref: 54-BIBP1075

Fmoc-6-aminohexanoic acid

CAS: 88574-06-5

Fmoc-6-aminohexanoic acid is an amino acid that can be used as a building block for peptides and proteins. It has a hydroxide group that can be reacted with other molecules in order to form a covalent bond. The compound reacts with sodium hydroxide solution to produce a particle that is soluble in water and organic solvents. Fmoc-6-aminohexanoic acid also inhibits the protease activity of subtilisin BPN' and leucine aminopeptidase, which are enzymes that break down proteins into smaller polypeptides. This material is functionalized with carboxyl groups on both ends, making it reactive and able to react with other molecules.

Formula: C₂₁H₂₃NO₄

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 353.41 g/mol

Ref: 3D-FF47372

Fmoc-ε-Acp-OH

CAS: 88574-06-5

Fmoc-6-aminohexanoic acid, a PROTAC linker, has a Fmoc-protected amine, carboxylic acid, and is used in conjugations.

Formula: C₂₁H₂₃NO₄

Color and Shape: Solid

Molecular weight: 353.41

Ref: TM-T71732