CAS 886214-18-2

Vercirnon sodium

CAS: 886214-18-2

Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.

Formula: C₂₂H₂₁ClN₂NaO₄S

Color and Shape: Solid

Molecular weight: 467.92

Ref: TM-T41016

Vercirnon sodium

CAS: 886214-18-2

Vercirnon sodium (VSN) is a peptide that belongs to the class of activators. It is a high-purity, water-soluble, and highly soluble peptide. VSN has been shown to inhibit ion channels by binding to their ligands or receptors. It also inhibits protein interactions by binding to the receptor that initiates the interaction with the ligand. VSN is a potent inhibitor of voltage-gated potassium channels, which are important in regulating nerve cell excitability. This inhibition leads to increased neuronal firing rates and reduced potassium channel availability in neurons, resulting in an overall increase in neuronal excitability.

Formula: C₂₂H₂₁ClN₂O₄S•Na

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 467.92 g/mol

Ref: 3D-LKB21418