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CAS 886762-09-0

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3-chloro-6-(trifluoromethyl)pyridin-2-amine

Description:
3-Chloro-6-(trifluoromethyl)pyridin-2-amine is an organic compound characterized by its pyridine ring, which is a six-membered aromatic heterocycle containing one nitrogen atom. The presence of a chloro group at the 3-position and a trifluoromethyl group at the 6-position significantly influences its chemical properties and reactivity. This compound is typically a solid at room temperature and may exhibit moderate solubility in polar organic solvents. Its trifluoromethyl group contributes to its lipophilicity and can enhance biological activity, making it of interest in pharmaceutical research. The chlorine atom can participate in nucleophilic substitution reactions, while the amino group at the 2-position can act as a hydrogen bond donor, influencing its interactions in biological systems. Overall, 3-chloro-6-(trifluoromethyl)pyridin-2-amine is a versatile compound with potential applications in medicinal chemistry and agrochemicals, owing to its unique structural features and functional groups.
Formula:C6H4ClF3N2
InChI:InChI=1/C6H4ClF3N2/c7-3-1-2-4(6(8,9)10)12-5(3)11/h1-2H,(H2,11,12)
SMILES:c1cc(C(F)(F)F)nc(c1Cl)N
Synonyms:
  • 2-Pyridinamine, 3-Chloro-6-(Trifluoromethyl)-
  • 3-Chloro-6-(trifluoromethyl)pyridin-2-amine
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