CAS 887258-94-8

Cyclopenta[4,5]pyrido[3,2,1-jk][1,4]benzodiazepine, 4,5,6,7,9,9a,10,11,12,12a-decahydro-, hydrochloride (1:1), (9aR,12aS)-

Description:

Cyclopenta[4,5]pyrido[3,2,1-jk][1,4]benzodiazepine, specifically the hydrochloride salt form with the CAS number 887258-94-8, is a complex organic compound characterized by its fused bicyclic structure that incorporates both benzodiazepine and pyridine moieties. This compound features a decahydro configuration, indicating a fully saturated ring system, which contributes to its unique chemical properties. The presence of the hydrochloride indicates that it is a salt formed with hydrochloric acid, enhancing its solubility in water and potentially influencing its pharmacological activity. The stereochemistry, denoted by the (9aR,12aS) designation, suggests specific spatial arrangements of atoms that can significantly affect the compound's biological interactions and efficacy. Such compounds are often investigated for their potential therapeutic applications, particularly in the fields of neuroscience and pharmacology, due to their ability to interact with neurotransmitter systems. Overall, this substance exemplifies the intricate relationship between molecular structure and biological function in medicinal chemistry.

Formula: C₁₅H₂₀N₂·ClH

InChI: InChI=1S/C15H20N2.ClH/c1-3-11-9-16-7-8-17-10-12-4-2-5-13(12)14(6-1)15(11)17;/h1,3,6,12-13,16H,2,4-5,7-10H2;1H/t12-,13-;/m0./s1

InChI key: InChIKey=PYPPENBDXAWXJC-QNTKWALQSA-N

SMILES: C1=2C=3N(C[C@]4([C@@]1(CCC4)[H])[H])CCNCC3C=CC2.Cl

Synonyms:

• Cyclopenta[4,5]pyrido[3,2,1-jk][1,4]benzodiazepine, 4,5,6,7,9,9a,10,11,12,12a-decahydro-, monohydrochloride, (9aR,12aS)-
• Cyclopenta[4,5]pyrido[3,2,1-jk][1,4]benzodiazepine, 4,5,6,7,9,9a,10,11,12,12a-decahydro-, hydrochloride (1:1), (9aR,12aS)-
• Vabicaserin hydrochloride
• SCA 136

Vabicaserin hydrochloride

CAS: 887258-94-8

Vabicaserin hydrochloride (SCA 136) is a selective agonist of 5-hydroxytryptamine 2C (5-HT2C) receptor (EC50: 8 nM).

Formula: C₁₅H₂₁ClN₂

Purity: 98.32%

Color and Shape: Solid

Molecular weight: 264.79

Ref: TM-T13275

Vabicaserin hydrochloride

CAS: 887258-94-8

Formula: C₁₅H₂₁ClN₂

Purity: 96%

Molecular weight: 264.7936

Ref: IN-DA01FHH7

Vabicaserin hydrochloride

CAS: 887258-94-8

Vabicaserin hydrochloride

Purity: ≥98%

Molecular weight: 264.79g/mol

Ref: 54-BUP12652

Vabicaserin Hydrochloride

CAS: 887258-94-8

Vabicaserin Hydrochloride

Purity: 97%

Molecular weight: 264.79g/mol

Ref: 54-OR1024028

Vabicaserin hydrochloride

CAS: 887258-94-8

Vabicaserin hydrochloride is a potent and selective 5-HT2C receptor antagonist. It is used as a treatment for obesity, type 2 diabetes, or neuropathic pain due to its effects on the serotonergic system. This drug inhibits the production of glucose by inhibiting the sodium-dependent glucose transporter in rat liver microsomes. Vabicaserin hydrochloride has been shown to inhibit the activity of 5-HT1A receptors in vitro assays and has an inhibitory effect on infectious diseases and autoimmune diseases. This drug also increases dopamine release in striatal tissues via inhibition of dopamine reuptake.

Formula: C₁₅H₂₁ClN₂

Purity: Min. 95%

Molecular weight: 264.79 g/mol

Ref: 3D-MKB25894