CAS 887258-95-9

(9aR,12aS)-4,5,6,7,9,9a,10,11,12,12a-Decahydrocyclopenta[4,5]pyrido[3,2,1-jk][1,4]benzodiazepine

Description:

The chemical substance known as (9aR,12aS)-4,5,6,7,9,9a,10,11,12,12a-Decahydrocyclopenta[4,5]pyrido[3,2,1-jk][1,4]benzodiazepine, with the CAS number 887258-95-9, is a complex bicyclic compound that belongs to the benzodiazepine class. This compound features a fused bicyclic structure that incorporates both a benzene ring and a diazepine moiety, contributing to its potential pharmacological properties. The stereochemistry indicated by the (9aR,12aS) designation suggests specific spatial arrangements of atoms, which can significantly influence the compound's biological activity and interactions with receptors. Typically, benzodiazepines are known for their effects on the central nervous system, often acting as anxiolytics, sedatives, or muscle relaxants. The unique structural features of this compound may confer distinct properties compared to other members of the benzodiazepine family, making it a subject of interest in medicinal chemistry and drug development. Further studies would be necessary to elucidate its specific biological activities and therapeutic potential.

Formula: C₁₅H₂₀N₂

InChI: InChI=1S/C15H20N2/c1-3-11-9-16-7-8-17-10-12-4-2-5-13(12)14(6-1)15(11)17/h1,3,6,12-13,16H,2,4-5,7-10H2/t12-,13-/m0/s1

InChI key: InChIKey=NPTIPEQJIDTVKR-STQMWFEESA-N

SMILES: C1=2C=3N(C[C@]4([C@@]1(CCC4)[H])[H])CCNCC3C=CC2

Synonyms:

• Cyclopenta[4,5]pyrido[3,2,1-jk][1,4]benzodiazepine, 4,5,6,7,9,9a,10,11,12,12a-decahydro-, (9aR,12aS)-
• (9aR,12aS)-4,5,6,7,9,9a,10,11,12,12a-Decahydrocyclopenta[4,5]pyrido[3,2,1-jk][1,4]benzodiazepine
• Vabicaserin

Vabicaserin Dihydrochloride

Controlled Product

CAS: 887258-95-9

Applications Vabicaserin Dihydrochloride is derived from N-Benzylaniline (B224940), which is a major metabolite of the antihistaminic Antazoline and other N-substituted benzylanilines.
References Ali, H.M. et al.: J. Chrom., 202, 287 (1980); Kucukguzel, I. et al.: J. Fac. Pharm. Istan. Univ., 32, 69 (1998);

Formula: C₁₅H₂₀N₂•2(HCl)

Color and Shape: Neat

Molecular weight: 264.13933

Ref: TR-V050005

Vabicaserin

CAS: 887258-95-9

Vabicaserin is a drug that belongs to the class of glycoside derivatives. It is an agonist of 5-HT2C receptors, which are located in the striatum and other parts of the brain. Vabicaserin has been shown to increase extracellular dopamine levels in the striatum. This drug has also been shown to have a therapeutic effect on chronic fatigue syndrome and other diseases involving inflammation of the nervous system. Vabicaserin has been shown to be effective against sodium-dependent glucose co-transporters 1 and 2 (SGLT1 and SGLT2) in human liver cells, which may lead to its use as a treatment for type 2 diabetes mellitus.

Formula: C₁₅H₂₀N₂

Purity: Min. 95%

Molecular weight: 228.33 g/mol

Ref: 3D-MKB25895