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CAS 88743-97-9

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Fmoc-Arg(Mts)-OH

Description:
Fmoc-Arg(Mts)-OH, with the CAS number 88743-97-9, is a chemical compound commonly used in peptide synthesis and research. It is a derivative of arginine, an amino acid, and features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized in solid-phase peptide synthesis to protect the amino group during the coupling reactions. The compound also contains a methanesulfonothioyl (Mts) group, which serves as a protecting group for the side chain of arginine, enhancing the selectivity and efficiency of peptide synthesis. Fmoc-Arg(Mts)-OH is typically characterized by its solid-state form, stability under standard laboratory conditions, and solubility in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). Its use is particularly valuable in the synthesis of peptides that require specific modifications or functionalization of the arginine residue, making it an important tool in the fields of biochemistry and medicinal chemistry.
Formula:C30H34N4O6S
InChI:InChI=1/C30H34N4O6S/c1-18-15-19(2)27(20(3)16-18)41(38,39)34-29(31)32-14-8-13-26(28(35)36)33-30(37)40-17-25-23-11-6-4-9-21(23)22-10-5-7-12-24(22)25/h4-7,9-12,15-16,25-26H,8,13-14,17H2,1-3H3,(H,33,37)(H,35,36)(H3,31,32,34)/t26-/m0/s1
SMILES:Cc1cc(C)c(c(C)c1)S(=O)(=O)NC(=N)NCCC[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12
Synonyms:
  • (E)-N~5~-(amino{[(2,4,6-trimethylphenyl)sulfonyl]amino}methylidene)-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine
  • -(mesitylene-2-sulfonyl)-L-arginine
  • N
  • L-Ornithine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N5-[imino[[(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-
  • FMOC-ARG(MTS)-OH
  • N-ALPHA-FMOC-N-G-(MESITYLENE-2-SULFONYL)-L-ARGININE
  • nα-fmoc-nω-(mesitylene-2-sulfonyl)-l-arginine
  • (2S)-5-[[Amino-[(2,4,6-trimethylphenyl)sulfonylamino]methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid
  • FMOC-N-OMEGA-(MESITYLENE-2-SULFONYL)-L-ARGININE
  • (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-[N'-(2,4,6-trimethylbenzenesulfonyl)carbamimidamido]pentanoic acid
  • See more synonyms
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