CAS 88795-32-8

Phenylmethyl (2S)-2-[[(2S)-2-formyl-1-pyrrolidinyl]carbonyl]-1-pyrrolidinecarboxylate

Description:

Phenylmethyl (2S)-2-[[(2S)-2-formyl-1-pyrrolidinyl]carbonyl]-1-pyrrolidinecarboxylate, with the CAS number 88795-32-8, is a chemical compound characterized by its complex structure featuring multiple functional groups. It contains a pyrrolidine ring, which is a five-membered nitrogen-containing heterocycle, and exhibits chirality due to the presence of stereocenters. The compound is likely to have both hydrophilic and hydrophobic characteristics due to the presence of carbonyl groups and aromatic rings, influencing its solubility and reactivity. Its structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, as compounds with pyrrolidine moieties are often associated with biological activity. The presence of the formyl group indicates potential for further chemical modifications, making it a versatile intermediate in organic synthesis. Additionally, the compound's stability and reactivity can be influenced by environmental factors such as pH and temperature, which are important considerations in its handling and application.

Formula: C₁₈H₂₂N₂O₄

InChI: InChI=1S/C18H22N2O4/c21-12-15-8-4-10-19(15)17(22)16-9-5-11-20(16)18(23)24-13-14-6-2-1-3-7-14/h1-3,6-7,12,15-16H,4-5,8-11,13H2/t15-,16-/m0/s1

InChI key: InChIKey=ORZXYSPOAVJYRU-HOTGVXAUSA-N

SMILES: C(=O)([C@H]1N(C(OCC2=CC=CC=C2)=O)CCC1)N3[C@H](C=O)CCC3

Synonyms:

• 1-Pyrrolidinecarboxylic acid, 2-[(2-formyl-1-pyrrolidinyl)carbonyl]-, phenylmethyl ester, [S-(R*,R*)]-
• Phenylmethyl (2S)-2-[[(2S)-2-formyl-1-pyrrolidinyl]carbonyl]-1-pyrrolidinecarboxylate
• Z-Prolyl-prolinal
• 1-Pyrrolidinecarboxylic acid, 2-[[(2S)-2-formyl-1-pyrrolidinyl]carbonyl]-, phenylmethyl ester, (2S)-
• N-Benzyloxycarbonyl-L-prolyl-L-prolinal

Z-Pro-prolinal

CAS: 88795-32-8

Z-Pro-prolinal, an orally active PREP inhibitor, IC50: 0.4 nM in porcine.

Formula: C₁₈H₂₂N₂O₄

Color and Shape: Solid

Molecular weight: 330.38

Ref: TM-T74044

Z-Pro-prolinal

CAS: 88795-32-8

Z-Pro-prolinal is a tetrapeptide that was discovered in a screening for enzyme inhibitors. It inhibits the activity of various enzymes, including angiotensin converting enzyme (ACE), endopeptidase, and proteinases. Z-Pro-prolinal has shown to have antihypertensive effects in rats with primary pulmonary hypertension. It has also been shown to inhibit the proteolytic activities of soybean trypsin and other enzymes.

Formula: C₁₈H₂₂N₂O₄

Purity: Min. 95%

Molecular weight: 330.4 g/mol

Ref: 3D-NDA79532