CAS 888-12-0

trans-2′-Hydroxychalcone

Description:

Trans-2′-Hydroxychalcone is a flavonoid compound characterized by its structural features, which include a chalcone backbone with a hydroxyl group at the 2' position of the aromatic ring. This compound typically exhibits a yellow to orange color due to its conjugated double bond system, which allows for light absorption in the visible spectrum. Trans-2′-Hydroxychalcone is known for its potential biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties. It is soluble in organic solvents and has limited solubility in water, which is common for many flavonoids. The compound's stability can be influenced by factors such as pH and light exposure, and it may undergo isomerization under certain conditions. In terms of applications, trans-2′-Hydroxychalcone is of interest in pharmaceutical and cosmetic formulations due to its beneficial effects on skin health and its role in various biochemical pathways. Its chemical reactivity and interactions with other molecules make it a subject of study in both synthetic and natural product chemistry.

Formula: C₁₅H₁₂O₂

InChI: InChI=1S/C15H12O2/c16-14-9-5-4-8-13(14)15(17)11-10-12-6-2-1-3-7-12/h1-11,16H/b11-10+

InChI key: InChIKey=AETKQQBRKSELEL-ZHACJKMWSA-N

SMILES: C(/C=C/C1=CC=CC=C1)(=O)C2=C(O)C=CC=C2

Synonyms:

• (2E)-1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one
• (2E)-1-(2-Hydroxyphenyl)-3-phenylprop-2-en-1-one
• (E)-1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one
• (E)-o-Hydroxyphenyl styryl ketone
• 1-(2-Hydroxyphenyl)-3-Phenylprop-2-En-1-One
• 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-phenyl-, (2E)-
• 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-phenyl-, (E)-
• Chalcone, 2′-hydroxy-, (E)-
• NSC 170284
• trans-2′-Hydroxychalcone

(E)-2'-Hydroxychalcone

CAS: 888-12-0

Formula: C₁₅H₁₂O₂

Purity: >98.0%(HPLC)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 224.26

Ref: 3B-H0385

(E)-2'-Hydroxychalcone

CAS: 888-12-0

(E)-2'-Hydroxychalcone

Formula: C₁₅H₁₂O₂

Purity: 0.96

Molecular weight: 224.25

Ref: 54-OR1130462

(E)-2'-Hydroxychalcone

CAS: 888-12-0

Formula: C₁₅H₁₂O₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 224.2546

Ref: IN-DA00GXUU

(2E)-1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one

Controlled Product

CAS: 888-12-0

Applications A synthetic chalcone with antibacterial and potential antitumoral activity.
References Echeveria, C. et al.: Int. J. Mol. Sci., 10, 221 (2009); Cabrera, M. et al.: Bioorg. Med. Chem., 18, 5391 (2010);

Formula: C₁₅H₁₂O₂

Color and Shape: Neat

Molecular weight: 224.25

Ref: TR-H949430