CAS 88889-14-9: Fosinopril sodium

Description:Fosinopril sodium is an angiotensin-converting enzyme (ACE) inhibitor primarily used in the treatment of hypertension and heart failure. It is a prodrug that is converted in the body to its active form, fosinoprilat, which inhibits the ACE enzyme, leading to decreased production of angiotensin II, a potent vasoconstrictor. This results in vasodilation, reduced blood pressure, and decreased workload on the heart. Fosinopril sodium is characterized by its unique structure, which includes a phosphinic acid group, contributing to its mechanism of action. It is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Common side effects may include dizziness, cough, and elevated potassium levels. As with other ACE inhibitors, it is contraindicated in pregnancy and should be used with caution in patients with renal impairment. Overall, fosinopril sodium is an effective medication for managing cardiovascular conditions, with a well-established safety profile when used appropriately.

Formula:C₃₀H₄₆NO₇P·Na

InChI:InChI=1S/C30H46NO7P.Na/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24;/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35);/t25-,26+,30+,39-;/m1./s1

InChI key:InChIKey=NIDZYXQFQSHBTG-WATAJHSMSA-N

SMILES:[Na].O=C(OC(OP(=O)(CC(=O)N1CC(CC1C(=O)O)C2CCCCC2)CCCCC=3C=CC=CC3)C(C)C)CC

Synonyms:
(4S)-4-Cyclohexyl-1-{[(RS)-2-methyl-1-(propionyloxy)propoxy]-(4-phenylbutyl)phosphinylacetyl}-L-proline sodium salt
(4S)-4-cyclohexyl-1-{[(R)-[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl}-L-proline
(4S)-4-cyclohexyl-1-{[{[(1S)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}-L-proline
L-Proline, 4-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt (1:1), (4S)-
L-Proline, 4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-
L-Proline, 4-cyclohexyl-1-[[[2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, [1[S*(R*)],2α,4β]-
Acecor
Eosinopril
Fosenopril sodium
Monopril
See more synonyms
Secorvas
Sq 28555
Staril
sodium (2S,4S)-4-cyclohexyl-1-({[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylate
sodium (2S,4S)-4-cyclohexyl-1-{[(R)-{[(1S)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}pyrrolidine-2-carboxylate
L-Proline, 4-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt (1:1), (4S)-
L-Proline, 4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-
Fosinopril sodium
L-Proline, 4-cyclohexyl-1-[[[2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, [1[S*(R*)],2α,4β]-

Found 15 products.

Product data	Purity	Price range	Estimated delivery
Fosinopril sodium CRS REF: 41-Y0001227CAS: 88889-14-9	- - -	115.00 €	Fri 02 May 25
Fosinopril sodium REF: 47-1091CAS: 88889-14-9	99.5%	242.00 €	Fri 02 May 25
Fosinopril Sodium REF: 45-1283404CAS: 88889-14-9	- - -	447.00 €	Mon 05 May 25
Fosinopril sodium REF: TM-T1489CAS: 88889-14-9	99.37% - 99.40%	34.00 €~207.00 €	Tue 06 May 25
L-Proline,4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)- REF: IN-DA00IFIBCAS: 88889-14-9	98%	To inquire	Tue 06 May 25
Fosinopril sodium salt REF: 4Z-F-121CAS: 88889-14-9	- - -	To inquire	Mon 05 May 25
Fosinopril Sodium REF: 54-OR1029490CAS: 88889-14-9	98%	32.00 €~2,303.00 €	Mon 05 May 25
Fosinopril sodium REF: 54-BUP11288CAS: 88889-14-9	≥98%	67.00 €~422.00 €	Mon 05 May 25
Fosinopril sodium salt REF: 7W-GP0614CAS: 88889-14-9	- - -	To inquire	Mon 05 May 25
Fosinopril-d5 Sodium Salt REF: 4Z-F-1218CAS: 88889-14-9	- - -	To inquire	Mon 05 May 25
Fosinopril Sodium REF: 86-MM0645.00-0250CAS: 88889-14-9	- - -	265.00 €	Wed 07 May 25
Fosinopril Sodium REF: 3B-F1242CAS: 88889-14-9	>98.0%(T)(HPLC)	156.00 €	Wed 07 May 25
Fosinopril Sodium Salt REF: TR-F727800CAS: 88889-14-9	- - -	107.00 €~252.00 €	Wed 14 May 25
Fosinopril sodium REF: 3D-FF23598CAS: 88889-14-9	Min. 98 Area-%	146.00 €~454.00 €	Thu 15 May 25
Fosinopril sodium salt - Bio-X ™ REF: 3D-BF164489CAS: 88889-14-9	Min. 95%	158.00 €	Thu 15 May 25