CAS 88889-14-9
:Fosinopril sodium
Description:
Fosinopril sodium is an angiotensin-converting enzyme (ACE) inhibitor primarily used in the treatment of hypertension and heart failure. It is a prodrug that is converted in the body to its active form, fosinoprilat, which inhibits the ACE enzyme, leading to decreased production of angiotensin II, a potent vasoconstrictor. This results in vasodilation, reduced blood pressure, and decreased workload on the heart. Fosinopril sodium is characterized by its unique structure, which includes a phosphinic acid group, contributing to its mechanism of action. It is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Common side effects may include dizziness, cough, and elevated potassium levels. As with other ACE inhibitors, it is contraindicated in pregnancy and should be used with caution in patients with renal impairment. Overall, fosinopril sodium is an effective medication for managing cardiovascular conditions, with a well-established safety profile when used appropriately.
Formula:C30H46NNaO7P
InChI:InChI=1/C30H46NO7P.Na/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24;/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35);/q;+1/p-1/t25-,26+,30+,39-;/m1./s1
InChI key:InChIKey=NIDZYXQFQSHBTG-WATAJHSMSA-N
SMILES:C(CP(O[C@H](OC(CC)=O)[C@@H](C)C)(CCCCC1=CC=CC=C1)=O)(=O)N2C[C@@H](C[C@H]2C(O)=O)[C@H]3CCCCC3.[Na]
Synonyms:- (4S)-4-Cyclohexyl-1-{[(RS)-2-methyl-1-(propionyloxy)propoxy]-(4-phenylbutyl)phosphinylacetyl}-L-proline sodium salt
- (4S)-4-cyclohexyl-1-{[(R)-[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl}-L-proline
- (4S)-4-cyclohexyl-1-{[{[(1S)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}-L-proline
- <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt (1:1), (4S)-
- <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-
- <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[[[2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, [1[S*(R*)],2α,4β]-
- Acecor
- Eosinopril
- Fosenopril sodium
- Monopril
- Secorvas
- Sq 28555
- Staril
- sodium (2S,4S)-4-cyclohexyl-1-({[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylate
- sodium (2S,4S)-4-cyclohexyl-1-{[(R)-{[(1S)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}pyrrolidine-2-carboxylate
- L-Proline, 4-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt (1:1), (4S)-
- L-Proline, 4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-
- Fosinopril sodium
- L-Proline, 4-cyclohexyl-1-[[[2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, [1[S*(R*)],2α,4β]-
- ELIDIUR
- (4S)-4-CYCLOHEXYL-1-[[(R)-[(1S)-2-METHYL-1-(1-OXOPROPOXY)PROPOXY](4-PHENYLBUTYL)PHOSPHINYL]ACETYL]-L-PROLINE
- 4β-Cyclohexyl-1-[[[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline sodium salt
- FOSINOPRIL-D5 SODIUM SALT
- FOSINOPRIL SODIUM SALT
- FOSINORM
- Forsinopril sodium salt
- FOSINOPRIL NA
- Dynacil, Elidiur, Fosinorm, Monopril, Staril, Tensozide, (4S)-4-Cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline
- TENSOZIDE
- FOSINPRIL SODIUM
- See more synonyms
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Found 15 products.
FOSINOPRIL SODIUM CRS
CAS:<p>FOSINOPRIL SODIUM CRS</p>Formula:C30H46NO7PColor and Shape:PowderMolecular weight:563.6625Fosinopril sodium
CAS:Fosinopril sodiumFormula:C30H45NNaO7PPurity:99.5%Color and Shape:Off-WhiteMolecular weight:585.28313Fosinopril Sodium
CAS:<p>Cardiovascular drugs, not elsewhere specified or includ</p>Formula:C30H45NO7PNaColor and Shape:PowderMolecular weight:585.28313L-Proline,4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-
CAS:Formula:C30H45NNaO7PPurity:98%Color and Shape:SolidMolecular weight:585.6443Fosinopril sodium
CAS:<p>Fosinopril sodium: ACE inhibitor prodrug for hypertension, becomes active metabolite fosinoprilat.</p>Formula:C30H45NO7P·NaPurity:99.37% - 99.40%Color and Shape:White To Off-White Crystalline SolidMolecular weight:585.65Fosinopril Sodium Salt
CAS:Formula:C30H45NO7P·NaColor and Shape:White To Off-White SolidMolecular weight:585.66Fosinopril-d5 Sodium Salt
CAS:Formula:C30H40D5NO7P·NaColor and Shape:White To Off-White SolidMolecular weight:567.70 22.99Fosinopril Sodium
CAS:Formula:C30H45NNaO7PPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:585.65Fosinopril Sodium Salt
CAS:<p>Applications A phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.<br>References Singhvi, S.M., et al.: Br. J. Clin. Pharmacol., 25, 9 (1988), Sullivan, P.A., et al.: Am. J. Hypertension, 1, 280S (1988),<br></p>Formula:C30H45NO7P·NaColor and Shape:NeatMolecular weight:585.64Fosinopril sodium
CAS:<p>Angiotensin converting enzyme inhibitor</p>Formula:C30H45NNaO7PPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:585.64 g/molFosinopril sodium salt - Bio-X ™
CAS:<p>Fosinopril belongs to the angiotensin-converting enzyme (ACE) inhibitor class of drugs, which prevents the conversion of angiotensin I to angiotensin II. This leads to decreases in blood pressure and slows down the progression of kidney disease, hypertension and heart failure.</p>Formula:C30H46NO7P•NaPurity:Min. 95%Color and Shape:PowderMolecular weight:586.65 g/mol
phosphinyl]ac…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00IFIB.jpg&w=3840&q=75)
